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Article

Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma

The Ewing sarcoma (ES) EWS-FLI1 chimeric oncoprotein is a prototypic aberrant ETS transcription factor with activating and repressive regulatory functions. We report that EWS-FLI1-repressed promoters are enric...

S Niedan, M Kauer, D N T Aryee, R Kofler, R Schwentner, A Meier, U Pötschger… in Oncogene (2014)