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Article
Sensitisation of c-MYC-induced B-lymphoma cells to apoptosis by ATF2
Transcription factors ATF2 (activating transcription factor 2) and ATF7 (activating transcription factor 7) are highly homologous members of the activator protein 1 (AP-1) family. Their activities are growth f...
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Article
Alcohol screening and brief intervention among drug users in primary care: a discussion paper
Problem alcohol use is common among problem drug users (PDU) and associated with adverse health outcomes. Primary care has an important role in the overall stepped approach to alcohol treatment, especially scr...
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Article
Open AccessIn vivo bioluminescence imaging of locally disseminated colon carcinoma in rats
Animal tumour models using orthotopic tumours for the evaluation of cancer therapies are of greater clinical relevance than subcutaneous models, but they also pose greater difficulties for measuring tumour siz...
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Article
Left ventricular hypertrophy and silent ischaemia: a pilot study to examine the relationship in hypertensive patients
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Article
Selected abstracts
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Article
Ammonium triggers calcium elevation in cultured mouse microglial cells by initiating Ca2+ release from thapsigargin-sensitive intracellular stores
Microglial cells are thought to serve as sensors for pathologic events in the brain. In the present study we demonstrate that these cells respond with an increase in intracellular calcium concentration ([Ca2+]i) ...
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Article
Body beautiful?
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Article
Can heart rate predict blood pressure response to anti-hypertensive drug therapy?
The use of heart rate in clinical practice is limited by its variability under measurement situations. The mean heart rate on ambulatory monitoring provides a more robust statistic for clinical use. We examine...
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Chapter and Conference Paper
Urothelial Cell Culture Behavior in Fibrin Glue Compared to Conventional Culture Medium
The modern field of tissue engineering has now successfully established cell cultures for nearly every tissue type of the human body including urothelium [1]. The next big step for a sophisticated defect repai...
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Article
IN VITRO ANALYSIS OF FUROSEMIDE DISPOSITION DURING NEONATAL EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) † 456
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Chapter and Conference Paper
Predictions of Turbulent Drag Reduction for a Linear Viscoelastic Fluid
A link between the decoupling of the Reynolds stress and the temporal relaxation of turbulent fluctuations, controlled by a finite propagation of momentum at small spatial scales, has been developed for turbul...
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Chapter
Modulation of T Cells and Macrophages by Cholera Toxin Treatment in Vivo and in Vitro
Cholera toxin (CT), the enterotoxin derived from pathogenic strains of Vibrio cholerae, is a potent modulator of immune responses, both in vivo and in vitro (1, 2, 5, 6, 7). Mice injected with CT simultaneously w...
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Article
IN VITRO ACTIVITY OF COMBINATIONS AMINOGLYCOSIDES AND PENICILLINS AGAINST GROUP B STREPTOCOCCI
In recent years group B streptococci (GBS) have become one of the most common etiologic agents in neonatal infections. In vitro studies indicate that GBS are susceptible to concentrations of penicillin and ampici...