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Article
Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: phase 1 results from the multicenter EVOLUTION study
This phase 1 study (Clinicaltrials.gov: NCT00507442) was conducted to determine the maximum tolerated dose (MTD) of cyclophosphamide in combination with bortezomib...
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Article
High incidence of graft failure in children receiving CD34+ augmented elutriated allografts for nonmalignant diseases
T-cell depletion of the marrow graft using counterflow centrifugal elutriation reduces the risk of graft-versus-host disease (GVHD). However, because of high rates of graft failure and relapse, elutriation alo...
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Chapter and Conference Paper
Cell Manipulation and Engineering — State of the Art and Future Developments
Within the last 5 years, the new field of somatic cell therapy (SCRx) has gone through exponential growth. This term was coined by the U.S.Food and Drug Administration (FDA) in guidance documents to encompass ...
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Chapter
Induction of Autologous Graft vs Host Disease: An Immunotherapeutic Approach to Eliminate Residual Leukemia After Autologous Bone Marrow Transplantation
Graft vs host disease (GVHD) remains a major complication following allogeneic bone marrow transplantation (BMT) [1]. The large number of peripheral blood T lymphocytes which contaminate the graft during bone ...