![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: phase 1 results from the multicenter EVOLUTION study
This phase 1 study (Clinicaltrials.gov: NCT00507442) was conducted to determine the maximum tolerated dose (MTD) of cyclophosphamide in combination with bortezomib...
-
Article
High incidence of graft failure in children receiving CD34+ augmented elutriated allografts for nonmalignant diseases
T-cell depletion of the marrow graft using counterflow centrifugal elutriation reduces the risk of graft-versus-host disease (GVHD). However, because of high rates of graft failure and relapse, elutriation alo...
-
Chapter and Conference Paper
Cell Manipulation and Engineering — State of the Art and Future Developments
Within the last 5 years, the new field of somatic cell therapy (SCRx) has gone through exponential growth. This term was coined by the U.S.Food and Drug Administration (FDA) in guidance documents to encompass ...
-
Article
Open AccessAutologous graft-versus-host disease induction in advanced breast cancer: role of peripheral blood progenitor cells
The purpose of the present study was to investigate the impact of the use of peripheral blood progenitor cells (PBPCs) on the induction of autologous graft-versus-host disease (GVHD) in patients with advanced ...
-
Chapter
Induction of Autologous Graft vs Host Disease: An Immunotherapeutic Approach to Eliminate Residual Leukemia After Autologous Bone Marrow Transplantation
Graft vs host disease (GVHD) remains a major complication following allogeneic bone marrow transplantation (BMT) [1]. The large number of peripheral blood T lymphocytes which contaminate the graft during bone ...
-
Chapter
Separation and Characterization of Guinea Pig Monocyte Subsets using Counter-Flow Centrifugation Elutriation (CCE)
Counter-flow centrifugation elutriation (CCE) has been used to separate human monocytes into two populations that differ in size, Fc receptors (FcR), antibody-dependent cellular cytotoxicity (ADCC), and native...