Skip to main content

and
  1. Article

    Open Access

    Early diagnosis and treatment of breast cancer in Japanese kidney transplant recipients: a single center experience

    The incidence of malignancies in kidney transplant recipients is increasing. Breast cancer is a common malignancy after kidney transplantation and can be more aggressive in kidney transplant recipients than in...

    Taigo Kato, Yoichi Kakuta, Kazuaki Yamanaka, Masayoshi Okumi, Toyofumi Abe in SpringerPlus (2015)

  2. Article

    Open Access

    Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent

    We have developed Si-based agent which can generate a large amount of hydrogen. Si-based agent continues generating hydrogen for more than 24 h by the reaction with water under conditions similar to those in b...

    Yuki Kobayashi, Ryoichi Imamura, Yoshihisa Koyama, Makoto Kondo in Scientific Reports (2020)

  3. Article

    Open Access

    Tumour grade significantly correlates with total dysfunction of tumour tissue-infiltrating lymphocytes in renal cell carcinoma

    It is important to evaluate the clinical importance of both CD8 T cells and CD4 T cells expression simultaneously because they have crucial networks in tumour targeting immune responses. In 97 RCC patients, RN...

    Atsunari Kawashima, Takayuki Kanazawa, Yujiro Kidani, Tetsuya Yoshida in Scientific Reports (2020)

  4. Article

    Open Access

    Serum phosphate levels modify the impact of parathyroid hormone levels on renal outcomes in kidney transplant recipients

    Separate assessment of mineral bone disorder (MBD) parameters including calcium, phosphate, parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D (1,2...

    Yohei Doi, Takayuki Hamano, Naotsugu Ichimaru, Kodo Tomida in Scientific Reports (2020)

  5. Article

    Open Access

    Bladder urothelium converts bacterial lipopolysaccharide information into neural signaling via an ATP-mediated pathway to enhance the micturition reflex for rapid defense

    When bacteria enter the bladder lumen, a first-stage active defensive mechanism flushes them out. Although urinary frequency induced by bacterial cystitis is a well-known defensive response against bacteria, t...

    Norichika Ueda, Makoto Kondo, Kentaro Takezawa, Hiroshi Kiuchi in Scientific Reports (2020)

  6. Article

    Open Access

    Decreased renal function increases the nighttime urine volume rate by carryover of salt excretion to the nighttime

    To determine the pathophysiology of nocturnal polyuria associated with renal dysfunction, patients who underwent laparoscopic nephrectomy were prospectively studied. The diurnal variation in urine volume, osmo...

    Kentaro Takezawa, Sohei Kuribayashi, Koichi Okada, Yosuke Sekii in Scientific Reports (2021)

  7. Article

    Open Access

    FAN score comprising fibrosis-4 index, albumin–bilirubin score and neutrophil–lymphocyte ratio is a prognostic marker of urothelial carcinoma patients treated with pembrolizumab

    It is important to identify prognostic and predictive markers of metastatic urothelial carcinoma (mUC) treated with immunocheckpoint inhibitors. We sought to establish a prognostic marker for patients with mUC...

    Atsunari Kawashima, Yoshiyuki Yamamoto, Mototaka Sato, Wataru Nakata in Scientific Reports (2021)