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  1. Article

    Open Access

    Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant

    Circulation of SARS-CoV-2 Omicron XBB has resulted in the emergence of XBB.1.5, a new Variant of Interest. Our phylogenetic analysis suggests that XBB.1.5 evolved from XBB.1 by acquiring the S486P spike (S) mu...

    Tomokazu Tamura, Takashi Irie, Sayaka Deguchi, Hisano Yajima in Nature Communications (2024)

  2. Article

    Open Access

    Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

    In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified, and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that XBB emerged through the recombination of two...

    Tomokazu Tamura, Jumpei Ito, Keiya Uriu, Jiri Zahradnik in Nature Communications (2023)

  3. Article

    Open Access

    Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

    The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern1. In this study, our statistical modelling suggests that Omicron has spread more rapidly than the Delta variant in several cou...

    Rigel Suzuki, Daichi Yamasoba, Izumi Kimura, Lei Wang, Mai Kishimoto, Jumpei Ito in Nature (2022)

  4. Article

    Open Access

    Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

    During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, at the time of ...

    Akatsuki Saito, Takashi Irie, Rigel Suzuki, Tadashi Maemura, Hesham Nasser in Nature (2022)