-
Article
Open AccessPyrotinib and trastuzumab plus palbociclib and fulvestrant in HR+/HER2+ breast cancer patients with brain metastasis
Human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) patients are at a high risk of develo** metastases in the brain. However, research focusing on treatment strategies for hormonal r...
-
Article
Open AccessGenetic analysis of oligo-recurrence breast cancer: correlation with clinical outcomes
We aimed to identify the relationship between the genomic characteristics and clinical outcomes of oligo-metastatic breast cancer.
-
Article
Open AccessThe prognostic value and immune microenvironment association of AR in HER2+ nonmetastatic breast cancer
This study aimed to investigate the prognostic value of AR in HER2+ nonmetastatic breast invasive ductal carcinoma (IDC) and its relationship with the immune microenvironment. HER2+ nonmetastatic breast IDC pa...
-
Article
Open AccessComorbidity in lung cancer patients and its association with hospital readmission and fatality in China
Comorbidity has been established as one of the important predictors of poor prognosis in lung cancer. In this study, we analyzed the prevalence of main comorbidities and its association with hospital readmissi...
-
Article
Open AccessComorbidity in lung cancer patients and its association with medical service cost and treatment choice in China
It is evident that comorbidity exacerbate the complexity of the management of lung cancer, however, limited research has been conducted to investigate the impact of comorbidity on health service utilization an...
-
Article
Open AccessErratum to: 53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells
-
Article
Open Access53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells
Mutations in DNA damage response factors BRCA1 and BRCA2 confer sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors in breast and ovarian cancers. BRCA1/BRCA2-defective tumors can exhibit resistance t...