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  1. Article

    Open Access

    Mesenchymal stem cell-derived extracellular vesicles alter disease outcomes via endorsement of macrophage polarization

    Mesenchymal stem cells (MSCs) are adult stromal cells that reside in virtually all postnatal tissues. Due to their regenerative and immunomodulatory capacities, MSCs have attracted growing attention during the...

    Jiangmei Wang, Jie **a, Ruoqiong Huang, Yaoqin Hu in Stem Cell Research & Therapy (2020)

  2. Article

    Open Access

    Functional proteins of mesenchymal stem cell-derived extracellular vesicles

    Extracellular vesicles (EVs) contain proteins, microRNAs, mRNAs, long non-coding RNAs, and phospholipids, and are a novel mechanism of intercellular communication. It has been proposed that the immunomodulator...

    Guanguan Qiu, Guo** Zheng, Menghua Ge, Jiangmei Wang in Stem Cell Research & Therapy (2019)

  3. Article

    Open Access

    Mesenchymal stem cell-derived extracellular vesicles affect disease outcomes via transfer of microRNAs

    Mesenchymal stem cells (MSCs) are adult stromal cells with the capacity to differentiate into multiple types of cells. MSCs represent an attractive option in regenerative medicine due to their multifaceted abi...

    Guanguan Qiu, Guo** Zheng, Menghua Ge, Jiangmei Wang in Stem Cell Research & Therapy (2018)

  4. No Access

    Article

    Mesenchymal stromal cell-derived extracellular vesicles: regenerative and immunomodulatory effects and potential applications in sepsis

    Mesenchymal stromal (stem) cells (MSCs) have multipotent differentiation capacity and exist in nearly all forms of post-natal organs and tissues. The immunosuppressive and anti-inflammatory properties of MSCs ...

    Guo** Zheng, Ruoqiong Huang, Guanguan Qiu, Menghua Ge in Cell and Tissue Research (2018)