4 Result(s)
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Article
Open AccessExtend the benchmarking indel set by manual review using the individual cell line sequencing data from the Sequencing Quality Control 2 (SEQC2) project
Accurate indel calling plays an important role in precision medicine. A benchmarking indel set is essential for thoroughly evaluating the indel calling performance of bioinformatics pipelines. A reference samp...
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Article
Open AccessAn intelligent recognition method of chromosome rearrangement patterns based on information entropy
Chromosome rearrangements play an important role in the speciation of plants and animals, and the recognition of chromosome rearrangement patterns is helpful to elucidate the mechanism of species differentiati...
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Article
Open AccessA comprehensive genomic and transcriptomic dataset of triple-negative breast cancers
Molecular subty** of triple-negative breast cancer (TNBC) is essential for understanding the mechanisms and discovering actionable targets of this highly heterogeneous type of breast cancer. We previously pe...
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Article
Open AccessRational design of heterodimeric receptors capable of activating target signaling molecules
Intracellular signal transduction is regulated by a variety of transmembrane receptors. Many researchers have aimed to arbitrarily regulate the intracellular signaling and subsequent cell fate with artificial ...
