12 Result(s)
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Ruo**g Huang
Life Sciences
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Article
Open AccessConstruction of the first high-density genetic linkage map and QTL map** of flavonoid and leaf-size related traits in Epimedium
Leaves are the main medicinal organ in Epimedium herbs, and leaf flavonoid content is an important criterion of Epimedium herbs. However, the underlying genes that regulate leaf size and flavonoid content are unc...
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Article
Open AccessSingle-cell transcriptome reveals cellular hierarchies and guides p-EMT-targeted trial in skull base chordoma
Skull base chordoma (SBC) is a bone cancer with a high recurrence rate, high radioresistance rate, and poorly understood mechanism. Here, we profiled the transcriptomes of 90,691 single cells, revealed the SBC...
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Article
Open AccessGenome-wide identification, evolutionary and expression analyses of LEA gene family in peanut (Arachis hypogaea L.)
Late embryogenesis abundant (LEA) proteins are a group of highly hydrophilic glycine-rich proteins, which accumulate in the late stage of seed maturation and are associated with many abiotic stresses. However,...
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Protocol
Enhanced Protein Profiling Arrays for High-Throughput Quantitative Measurement of Cytokine Expression
The antibody array has become a powerful technology in recent years and is widely used to detect the expression levels of various proteins such as cytokines, growth factors, chemokines, and angiogenic factors,...
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Protocol
Methods for Membranes and Other Absorbent Surfaces
Membrane arrays are a unique array platform option for the detection of multiple analytes or materials simultaneously. Their naturally absorptive properties and near universal use in various laboratory methods...
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Protocol
Global Detection of Proteins by Label-Based Antibody Array
Because of narrow availability of antibody pairs and potential cross-reactivity between antibodies, the development of sandwich-based antibody arrays which need a pair of antibodies for each target has been re...
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Article
Open AccessMesenchymal stem cell-derived extracellular vesicles alter disease outcomes via endorsement of macrophage polarization
Mesenchymal stem cells (MSCs) are adult stromal cells that reside in virtually all postnatal tissues. Due to their regenerative and immunomodulatory capacities, MSCs have attracted growing attention during the...
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Article
SspABCD–SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities
Bacteria have evolved diverse mechanisms to fend off predation by bacteriophages. We previously identified the Dnd system, which uses DndABCDE to insert sulfur into the DNA backbone as a double-stranded phosph...
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Article
Open AccessFunctional proteins of mesenchymal stem cell-derived extracellular vesicles
Extracellular vesicles (EVs) contain proteins, microRNAs, mRNAs, long non-coding RNAs, and phospholipids, and are a novel mechanism of intercellular communication. It has been proposed that the immunomodulator...
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Open AccessMesenchymal stem cell-derived extracellular vesicles affect disease outcomes via transfer of microRNAs
Mesenchymal stem cells (MSCs) are adult stromal cells with the capacity to differentiate into multiple types of cells. MSCs represent an attractive option in regenerative medicine due to their multifaceted abi...
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Article
Open AccessIntegrated metagenomic data analysis demonstrates that a loss of diversity in oral microbiota is associated with periodontitis
Periodontitis is an inflammatory disease affecting the tissues supporting teeth (periodontium). Integrative analysis of metagenomic samples from multiple periodontitis studies is a powerful way to examine micr...
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Article
ERCC1 expression as a prognostic and predictive factor in patients with non-small cell lung cancer: a meta-analysis
It is hypothesized that high expression of the excision repair cross-complementation group 1 (ERCC1) gene might be a positive prognostic factor, but predict decreased sensitivity to platinum-based chemotherapy...
