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  1. Article

    Open Access

    An ENU-induced mutation in Twist1 transactivation domain causes hindlimb polydactyly with complete penetrance and dominant-negatively impairs E2A-dependent transcription

    Twist1 encodes a basic helix-loop-helix transcription factor (TF), which forms homodimer or heterodimer with other TFs, like E2A, to regulate target genes’ expression. Mutations in TWIST1 are associated with Saet...

    Run-Ze Chen, Xuebo Cheng, Yuexi Tan, Tien-Chien Chang, Hailong Lv… in Scientific Reports (2020)

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  2. No Access

    Article

    Structural basis for RNA recognition by a dimeric PPR-protein complex

    Pentatricopeptide repeat (PPR) proteins are involved in different RNA processes, but how they recognize their target RNAs has been unclear. Now crystal structures of plant PPR protein–THA8 in complex with RNA,...

    Jiyuan Ke, Run-Ze Chen, Ting Ban, X Edward Zhou… in Nature Structural & Molecular Biology (2013)

  3. Article

    Open Access

    Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14

    Li-Hua Zhao, X Edward Zhou, Zhong-Shan Wu, Wei Yi, Yong Xu, Suling Li… in Cell Research (2013)

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