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Article
Open AccessNeointimal hyperplasia persists at six months after sirolimus-eluting stent implantation in diabetic porcine
Observational clinical studies have shown that patients with diabetes have less favorable results after percutaneous coronary intervention compared with the non-diabetic counterparts, but its mechanism remains...
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Article
Nrf2 activity is lost in the spinal cord and its astrocytes of aged mice
We report herein a study of aging using in vitro and in vivo models. Glial fibrillary acidic protein and ferritin expression levels increased, and the levels of glutamate transporter 1 and transferrin receptor...
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Article
In vitro and in vivo antileishmanial efficacy of nitazoxanide against Leishmania donovani
Control of Leishmania infection relies primarily on chemotherapy, and the current drug available for treating leishmaniasis is limited. Nitazoxanide (NTZ) is a broad spectrum antiparasitic agent with activity aga...
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Article
Open AccessChromosome 9p21.3 polymorphism in a Chinese Han population is associated with angiographic coronary plaque progression in non-diabetic but not in type 2 diabetic patients
We sought to explore the association of variant rs1333049 on chromosome 9p21.3 with coronary artery disease (CAD) and angiographic plaque progression in non-diabetic and type 2 diabetic patients.
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Article
Open AccessPlasma concentrations of osteopontin, but not thrombin-cleaved osteopontin, are associated with the presence and severity of nephropathy and coronary artery disease in patients with type 2 diabetes mellitus
The aim of the present cross-sectional study was to assess possible associations between osteopontin (OPN), and thrombin-cleaved (N-half) OPN, and nephropathy and coronary artery disease (CAD) in patients with...
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Article
Open AccessSimultaneous feature selection and classification via Minimax Probability Machine
This paper presents a novel method for simultaneous feature selection and classification by incorporating a robust L1-norm into the objective function of Minimax Probability Machine (MPM). A fractional programmin...
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Article
Open AccessInsulin resistance predicts progression of de novo atherosclerotic plaques in patients with coronary heart disease: a one-year follow-up study
The aim of our study was to explore and evaluate the relationship between insulin resistance and progression of coronary atherosclerotic plaques. With the great burden coronary heart disease is imposing on ind...
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Article
Open AccessThe effects of low-dose Nepsilon-(carboxymethyl)lysine (CML) and Nepsilon-(carboxyethyl)lysine (CEL), two main glycation free adducts considered as potential uremic toxins, on endothelial progenitor cell function
Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD). Endothelial progenitor cell (EPCs) dysfunction plays a key role in this pathogenesis. Uremic retention toxins have b...
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Chapter and Conference Paper
A Study and Application of Optimization on Console Development
Objectives The purpose of this paper is to study optimization methods and apply them to automobile plastic parts development. With the floor console development as an example, some optimization methods have been ...
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Article
Open AccessTetranectin as a Potential Biomarker for Stable Coronary Artery Disease
This cross-sectional study tested the hypothesis that decreased serum levels of tetranectin (TN), a regulator of the fibrinolysis and proteolytic system, is associated with the presence and severity of CAD. We...
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Article
Open AccessProkineticin-2 is associated with metabolic syndrome in a middle-aged and elderly Chinese population
Prokineticin-2 is confirmed to be involved in the inflammatory process. Inflammation plays an important role in the pathogenesis of metabolic syndrome (MS). However, whether prokineticin-2 is associated with M...
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Article
Open AccessLow serum calcium is associated with left ventricular systolic dysfunction in a Chinese population with coronary artery disease
Whether serum calcium is associated with heart systolic function in patients with established coronary artery disease (CAD) and acute myocardial infarction (AMI) remains to be elucidated. This study is aimed t...
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Article
p-Cresyl sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular smooth muscle cells
Coronary atherosclerosis is a major complication of chronic kidney disease. This condition contributes to the increased mortality in dialysis patients. p-Cresyl sulfate (PCS) is a prototype of protein-bound uremi...
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Article
Open AccessIL-34 is associated with the presence and severity of renal dysfunction and coronary artery disease in patients with heart failure
Pro-inflammatory mediators are identified in patients with heart failure (HF), some of which may be used as biomarkers with diagnostic or prognostic value. As an additional ligand of Colony Stimulating Factor-...
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Article
Safety and efficacy of a novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent
Late stent thrombosis (LST) following drug-eluting stent (DES) implantation in patients with coronary artery disease (CAD) is often associated with delayed vascular healing, resulting from vascular inflammatio...
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Article
The first record of Porcellanaster ceruleus (Echinodermata: Porcellanasteridae) in the South China Sea
Porcellanasteridae is a group of starfish that live in the deep ocean around the world. The type species of this family, Porcellanaster ceruleus Wyville Thomson, 1878, is cosmopolitan as well as polymorphic. The ...
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Chapter and Conference Paper
Deep Local-Global Refinement Network for Stent Analysis in IVOCT Images
Implantation of stents into coronary arteries is a common treatment option for patients with cardiovascular disease. Assessment of safety and efficacy of the stent implantation occurs via manual visual inspect...
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Article
Different vertical distribution of zooplankton community between North Pacific Subtropical Gyre and Western Pacific Warm Pool: its implication to carbon flux
The mesozooplankton in both epipelagic and mesopelagic zones is essentially important for the study of ecosystem and biological carbon pump. Previous studies showed that the diel vertical migration (DVM) patte...
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Article
Open AccessSerum sLYVE-1 is not associated with coronary disease but with renal dysfunction: a retrospective study
Recent evidence has indicated that the lymphatic vessel endothelial hyaluronan receptor (LYVE-1) is implicated in chronic inflammation and the lymphatic immune response. The soluble form of LYVE-1 (sLYVE-1) is...
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Chapter and Conference Paper
Prediction of Pressure Drop in Adsorption Filter Using Friction Factor Correlations for Packed Bed
Adsorption filters in air cleaners are usually produced as honeycomb structure filled with granular adsorbent, which can be seen as numerous parallel arranged fixed beds. In order to investigate if the frictio...
