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Article
Open AccesscircSORBS1 inhibits lung cancer progression by sponging miR-6779-5p and directly binding RUFY3 mRNA
Lung cancer is the primary cause of cancer-related death worldwide, and its global incidence and mortality rates remain high. The differential expression of circular RNAs (circRNAs) can affect the development ...
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Article
Open AccessA divergent intermediate strategy yields biologically diverse pseudo-natural products
The efficient exploration of biologically relevant chemical space is essential for the discovery of bioactive compounds. A molecular design principle that possesses both biological relevance and structural div...
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Article
Systematic Analysis of the Relationship Between Elevated Zinc and Epilepsy
Previous studies have indicated a potential relationship between zinc and epilepsy. The aim of this study is to investigate the causal relationship between zinc, zinc-dependent carbonic anhydrase, and gray mat...
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Article
Open AccessUnraveling the Fundamental Mechanism of Interface Conductive Network Influence on the Fast-Charging Performance of SiO-Based Anode for Lithium-Ion Batteries
Influence of interface conductive network on ionic transport and mechanical stability under fast charging is explored for the first time.
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Article
Exosomal circCNOT6L Regulates Astrocyte Apoptotic Signals Induced by Hypoxia Exposure Through miR99a-5p/SERPINE1 and Alleviates Ischemic Stroke Injury
Circular RNAs are involved in intervention strategies for treating ischemic stroke (IS). However, circCNOT6L (hsa_circ_0006168) has not yet been reported in IS. Thus, we aimed to explore the potential role of ...
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Article
Identification and expression profiles of candidate chemoreceptor genes in the tea leafhopper, Empoasca onukii Matsuda (Hemiptera: Cicadellidae)
The olfactory system of insects regulates the processes of insect feeding, mating, and egg laying through the participation of various olfactory proteins, hence it plays a key role in insect survival and repro...
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Article
Fabrication of CdxZn1−xS@VPO (x = 0.2) Nanocomposites for n-Butane Selective Oxidation Toward Maleic Anhydride
Vanadium phosphorous oxide (VPO) catalysts have been recognized as heterogeneous catalyst for selective oxidation of low-carbon alkanes i.e., n-butane toward maleic anhydride. This process has widely gained atten...
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Article
Administration of necrostatin-1 ameliorates glucocorticoid-induced osteonecrosis of the femoral head in rats
Glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH) is a serious complication of glucocorticoid treatment and is characterized by dysfunctional bone reconstruction at necrotic sites. Our previ...
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Article
A novel ratiometric fluorescence probe for the detection of copper (II) and silver(I) based on assembling dye-doped silica core–shell nanoparticles with gold nanoclusters
A creatively designed and constructed a multifunctional ratiometric fluorescence probe is reported by assembling glutathione (GSH)-protected gold nanoclusters (AuNCs) with fluorescein-doped mesoporous silica n...
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Chapter and Conference Paper
Robust Ego-Velocity Estimate Method Based on GNSS and Stereo Visual Sensor Fusion in Variable-Rate Application for Agricultural Vehicles
A stable ego-velocity estimate method by integrating a low-cost single global navigation satellite system (GNSS) and stereo visual sensor is proposed in this study, to address the problem of vehicle velocity m...
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Article
Amorphous copper cobalt carbonate hydroxide prepared by SILAR on copper foam for non-enzymatic glucose sensing
Amorphous copper cobalt carbonate hydroxide (CuCoCH) was prepared on copper foam (CF) by successive ionic layer adsorption and reaction (SILAR) method for non-enzymatic glucose sensing. The binder-free approac...
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Article
Dual Nature Cupper-Based Ionic Liquid-Assisted n-Butane Selective Oxidation with a Vanadium Phosphorus Oxide Catalyst
Recently, global warming is proving to be an increasing challenge for the sustainable human survival on planet earth. Worldwide, researchers are putting their efforts into controlling carbon emissions and have...
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Article
Molecular Structure and Supramolecular Architecture of Brivanib: (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f] [1,2,4]triazin-6-yloxy)propan-2-ol
Crystal structure of brivanib ((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-ol) is reported for the first time. Crystallographic parameters for brivanib: M =...
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Article
Open AccessEvaluation of the competitiveness of the container multimodal port hub
The research on the competitiveness of container multimodal transport port hub, comprehensively considering the software and hardware strength of port hub, is of great significance to analyze the specific sour...
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Article
sVCAM1 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Mice by Inducing Microglial Activation Through the VLA-4 Receptor
Postoperative cognitive dysfunction (POCD) is a severe postsurgical complication, but its underlying mechanisms remain unclear. Neuroinflammation mediated by microglial activation plays a major role in POCD pa...
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Article
Apigenin inhibits growth of melanoma by suppressing miR-512-3p and promoting the G1 phase of cell cycle involving the p27 Kip1 protein
In the present study, we screened multiple melanoma cell lines for treatment of Apigenin and miRNA expression, also studied the role of miR-512-3p in melanoma. RT-PCR analysis was done for screening miRNA in m...
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Article
Open AccessIdentification of co-expression hub genes for ferroptosis in kidney renal clear cell carcinoma based on weighted gene co-expression network analysis and The Cancer Genome Atlas clinical data
Renal clear cell carcinoma (KIRC) is one of the most common tumors worldwide and has a high mortality rate. Ferroptosis is a major mechanism of tumor occurrence and development, as well as important for progno...
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Article
Open AccessCircular RNA circGLIS3 promotes bladder cancer proliferation via the miR-1273f/SKP1/Cyclin D1 axis
Extensive research confirmed that circRNA can play a regulatory role in various stages of tumors by interacting with various molecules. Identifying the differentially expressed circRNA in bladder cancer and ex...
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Article
Circ_0007121 Facilitates Trophoblastic Cell Proliferation, Migration, and Invasion via the Regulation of the miR-421/ZEB1 Axis in Preeclampsia
Noncoding circular RNAs (circRNAs) have participated in the progression of preeclampsia (PE) via inhibiting microRNAs (miRNAs) to regulate gene expression. This study was designed to explore the miRNA/mRNA mec...
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Chapter and Conference Paper
Policy Evaluation of Construction Waste Resource Utilisation Based on S-CAD Method: Taking Shandong as an Example
Scientific policy evaluation is not only the measure of the effectiveness of policy implementation, but also the periodic summary of policy application, so as to provide a basis for subsequent policy revision....
