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Open AccessPrevalence and risk factors of sarcopenia in patients on maintenance hemodialysis: a retrospective cohort study
This study aimed to explore the prevalence and related risk factors of sarcopenia in patients on maintenance hemodialysis (MHD).
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Open AccessExploring the nexus between fatigue, body composition, and muscle strength in hemodialysis patients
Fatigue is a relatively prevalent condition among hemodialysis patients, resulting in diminished health-related quality of life and decreased survival rates. The purpose of this study was to investigate the re...
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Open AccessDiosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation
Renal fibrosis is considered an irreversible pathological process and the ultimate common pathway for the development of all types of chronic kidney diseases and renal failure. Diosmin is a natural flavonoid g...
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Open AccessMultifunctional mesoporous silica nanoparticles for biomedical applications
Mesoporous silica nanoparticles (MSNs) are recognized as a prime example of nanotechnology applied in the biomedical field, due to their easily tunable structure and composition, diverse surface functionalizat...
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Article
Early evaluation of severe immune checkpoint inhibitor-associated myocarditis: a real-world clinical practice
Immune checkpoint inhibitor (ICI)-associated myocarditis is a rare but severe complication for patients treated with immunotherapy. This study aims to explore the predictive significance of patients’ clinical ...
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Open AccessAnalysis of the potential biological mechanisms of diosmin against renal fibrosis based on network pharmacology and molecular docking approach
Interstitial fibrosis is involved in the progression of various chronic kidney diseases and renal failure. Diosmin is a naturally occurring flavonoid glycoside that has antioxidant, anti-inflammatory, and anti...
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Open AccessClinical application of liquid biopsy in endometrial carcinoma
Endometrial cancer is the most common gynecological malignant tumor in women, and its morbidity and mortality have been rising in recent years. Over the past two decades, the diagnosis, prognosis, and therapeu...
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Cardiac magnetic resonance T1 map** for evaluating myocardial fibrosis in patients with type 2 diabetes mellitus: correlation with left ventricular longitudinal diastolic dysfunction
We aimed to evaluate myocardial fibrosis using cardiac magnetic resonance (CMR) T1 map** in type 2 diabetes mellitus (T2DM) patients and investigate the association between left ventricular (LV) subclinical ...
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Open AccessA non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants
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Association of serum apolipoprotein B with retinal neurovascular structural alterations in patients with type 2 diabetes: an optical coherence tomography angiography study
To investigate the association of serum apoB concentrations with retinal neurovascular structural alterations in type 2 diabetes patients without clinically visible retinopathy.
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Open AccessCharacteristics of coronary artery disease in patients with subclinical hypothyroidism: evaluation using coronary artery computed tomography angiography
Subclinical hypothyroidism (SCH) has recently been acknowledged as an independent risk factor for coronary artery disease (CAD). However, the characteristics of CAD in patients with SCH are not fully understoo...
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Open AccessIdentification of a hotspot on PD-L1 for pH-dependent binding by monoclonal antibodies for tumor therapy
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Open AccessDose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults
There is uncertain evidence in the dose-response association between overall physical activity levels and clustering of cardiovascular diseases modifiable risk factors (CVDMRF) in Chinese adults. This study ex...
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Open AccessThe identification of a CD47-blocking “hotspot” and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination
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Expression of concern: Short hairpin RNA (shRNA) of type 2 interleukin-1 receptor (IL1R2) inhibits the proliferation of human osteosarcoma U-2 OS cells
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Open AccessLiver tumor boundaries identified intraoperatively using real-time indocyanine green fluorescence imaging
Clear delineation between tumors and normal tissues is ideal for real-time surgical navigation imaging. We investigated applying indocyanine green (ICG) fluorescence imaging navigation using an intraoperative ...
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Short hairpin RNA (shRNA) of type 2 interleukin-1 receptor (IL1R2) inhibits the proliferation of human osteosarcoma U-2 OS cells
Type 2 interleukin-1 receptor (IL1R2) is a member of the IL1 family. It has been reported that IL1R2 is expressed and plays important roles in several cancers. However, its potential role in human osteosarcoma...