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Article
Effects of cisplatin on telomerase activity and telomere length in BEL-7404 human hepatoma cells
Telomerase activity was inhibited in a dose and time-dependent manner with the treatment of cisplatin for 24, 48, or 72 h in a concentration ranged from 0.8 to 50 μM in BEL-7404 human hepatoma cells. There were n...
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Article
Surgical treatment of primary esophageal small-cell carcinoma
Objective: To study the clinical biocharacteristics of primary esophageal small-cell carcinoma (PESC) and factors influencing prognosis and to find rational indications for combination therapy. Methods: To ana...
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Article
Using a non-radioisotopic, quantitative TRAP-based method detecting telomerase activities in human hepatoma cells
A non-radioisotopic, quantitative TRAP-based telomerase activity assay was established mainly by using SYBR Green-I staining instead of radioisotope. Comparing with conventional radioisotope based method, it w...
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Article
Telomerase: A novel target of antitumor agents
Telomerase activity was found to be high in various human cancers, but absent in most normal tissues. Its expression pattern made it a novel target for antitumor agents. Several strategies against telomerase w...
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Article
Surgical treatment of primary esophageal adenocarcinoma
Objective: To study the biocharacteristics of primary esophageal adenocarcinoma (PEAC) and factors influencing patients’ prognosis and to find rational surgical indications and combined therapy. Methods: To an...
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Chapter and Conference Paper
Late Results of Surgical Treatment for Carcinoma of the Esophagus
In 1981 we reported our experience in the surgical treatment of 1647 patients with carcinoma of the esophagus during a 22-year period from 1958 through 1979 [1]. A further follow-up study of this series of cas...
