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  1. Article

    Open Access

    Pre-clinical quantitative imaging and mouse-specific dosimetry for 111In-labelled radiotracers

    Accurate quantification in molecular imaging is essential to improve the assessment of novel drugs and compare the radiobiological effects of therapeutic agents prior to in-human studies. The aim of this study...

    Ana M. Denis-Bacelar, Sarah E. Cronin, Chiara Da Pieve, Rowena L. Paul… in EJNMMI Research (2016)

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  2. Article

    Open Access

    Synthesis and biological evaluation of [18F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter

    The human sodium/iodide symporter (hNIS) is a well-established target in thyroid disease and reporter gene imaging using gamma emitters 123I-iodide, 131I-iodide and 99mTc-pertechnetate. However, no PET imaging ag...

    Maite Jauregui-Osoro, Kavitha Sunassee… in European Journal of Nuclear Medicine and M… (2010)

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  3. No Access

    Article

    Radiobiological effects of hypoxia-dependent uptake of 64Cu-ATSM: enhanced DNA damage and cytotoxicity in hypoxic cells

    Hypoxia occurs frequently in cancers and can lead to therapeutic resistance due to poor perfusion and loss of the oxygen enhancement effect. 64Cu-ATSM has shown promise as a hypoxia diagnostic agent due to its se...

    Amanda J. Weeks, Rowena L. Paul… in European Journal of Nuclear Medicine and M… (2010)