7 Result(s)

Article

MT1G induces lipid droplet accumulation through modulation of H3K14 trimethylation accelerating clear cell renal cell carcinoma progression

Lipid droplet formation is a prominent histological feature in clear cell renal cell carcinoma (ccRCC), but the significance and mechanisms underlying lipid droplet accumulation remain unclear.

Sen Wang, Kexin Wang, Dong Yue, **axia Yang, **aozao Pan… in British Journal of Cancer (2024)

Article

Correction: AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination

Rou Zhao, Baoyu He, Qingli Bie, **ghe Cao… in Journal of Experimental & Clinical Cancer … (2022)

Article

AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination

Cancer stem cells (CSCs) are regarded as the "seed cells" for tumorigenesis, metastasis, recurrence and drug resistance. However, specific surface markers of CSCs of different origins have not been documented.

Rou Zhao, Baoyu He, Qingli Bie, **ghe Cao… in Journal of Experimental & Clinical Cancer … (2022)

Article

Long noncoding RNA LINC00930 promotes PFKFB3-mediated tumor glycolysis and cell proliferation in nasopharyngeal carcinoma

Metabolic reprogramming is a hallmark of cancer. However, the roles of long noncoding RNAs (lncRNAs) in cancer metabolism, especially glucose metabolism remain largely unknown.

Baoyu He, Hongli Pan, Fengque Zheng… in Journal of Experimental & Clinical Cancer … (2022)

Article

IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination

Cancer stem cells (CSCs) are characterized by robust self-renewal and tumorigenesis and are responsible for metastasis, drug resistance, and angiogenesis. However, the molecular mechanisms for the regulation o...

Qingli Bie, Hui Song, **nke Chen, **ao Yang, Shuo Shi, Lihua Zhang, Rou Zhao… in Oncogene (2021)