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  1. No Access

    Chapter

    Ototoxicity After Childhood Cancer

    Ototoxicity (i.e., toxic damage to the ear) is a side effect of many drugs that are used in cancer treatment, including anticancer drugs and co-medication such as aminoglycoside antibiotics, glycopeptide antib...

    Amélie Tillmanns, Claudia Lanvers-Kaminsky… in Late Treatment Effects and Cancer Survivor… (2021)

  2. No Access

    Article

    Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: The International PanCareLIFE Study

    Ototoxicity is a common side effect of platinum treatment and manifests as irreversible, high-frequency sensorineural hearing loss. Genetic association studies have suggested a role for SNPs in genes related t...

    Eva Clemens, Linda Broer, Thorsten Langer… in The Pharmacogenomics Journal (2020)

  3. No Access

    Chapter

    Basics of Disorders of Hearing Development

    After the definition of hearing loss, audiological grading scales defining the presence and severity of hearing loss are presented. An overview is provided of epidemiological estimates of childhood hearing los...

    Antoinette am Zehnhoff-Dinnesen, Wendy Albuquerque, Hanno J. Bolz… in Phoniatrics I (2020)

  4. No Access

    Chapter

    Diagnosis and Differential Diagnosis of Disorders of Hearing Development

    Specific history-taking, drawing a family tree and thorough clinical examination are explained in detail. Standards and calibration in audiometry are presented. Pure-tone audiometry (PTA) and principles of mas...

    Ahmet Atas, Songul Aksoy, Antoinette am Zehnhoff-Dinnesen… in Phoniatrics I (2020)

  5. No Access

    Chapter

    Rehabilitation and Prognosis of Disorders of Hearing Development

    The prognosis of childhood hearing impairment depends upon the type of hearing disorder diagnosed, its severity and time of onset, the time points at which the hearing impairment was detected and treatment beg...

    Songul Aksoy, Antoinette am Zehnhoff-Dinnesen, Ahmet Atas… in Phoniatrics I (2020)

  6. No Access

    Chapter

    Special Kinds of Disorders of Hearing Development

    An overview presenting the types and courses of hearing loss is followed by descriptions of special kinds of hearing impairment. Mechanisms and aetiologies are outlined in this chapter.

    Antoinette am Zehnhoff-Dinnesen, Doris-Eva Bamiou, Nicole G. Campbell… in Phoniatrics I (2020)

  7. No Access

    Chapter

    Prevention of Disorders of Hearing Development

    Universal newborn hearing screening (UNHS) has turned out to be the most effective way to identify congenital paediatric sensorineural hearing loss. Screening principles and methods, possible screening failure...

    Antoinette am Zehnhoff-Dinnesen, Hanno J. Bolz, Gwen Carr, Manfred Gross✝… in Phoniatrics I (2020)

  8. No Access

    Article

    Impact of radiation technique, radiation fraction dose, and total cisplatin dose on hearing

    To analyze the incidence and degree of sensorineural hearing loss (SNHL) resulting from different radiation techniques, fractionation dose, mean cochlear radiation dose (Dmean), and total cisplatin dose.

    Sergiu Scobioala MD, Ross Parfitt, Peter Matulat… in Strahlentherapie und Onkologie (2017)