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  1. Article

    Open Access

    Experimental validation of methods for differential gene expression analysis and sample pooling in RNA-seq

    Massively parallel cDNA sequencing (RNA-seq) experiments are gradually superseding microarrays in quantitative gene expression profiling. However, many biologists are uncertain about the choice of differential...

    Anto P. Rajkumar, Per Qvist, Ross Lazarus, Francesco Lescai, Jia Ju in BMC Genomics (2015)

  2. Article

    Open Access

    Comparison of linkage and association strategies for quantitative traits using the COGA dataset

    Genome scans using dense single-nucleotide polymorphism (SNP) data have recently become a reality. It is thought that the increase in information content for linkage analysis as a result of the denser scans wi...

    Matthew B McQueen, Amy Murphy, Peter Kraft, Jessica Su, Ross Lazarus in BMC Genetics (2005)

  3. Article

    Open Access

    Genomic screening in family-based association testing

    Due to the recent gains in the availability of single-nucleotide polymorphism data, genome-wide association testing has become feasible. It is hoped that this additional data may confirm the presence of diseas...

    Amy Murphy, Matthew B McQueen, Jessica Su, Peter Kraft, Ross Lazarus in BMC Genetics (2005)