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Article
Open AccessEffect of ethnic diversity on the saccadic reaction time among healthy Indian and Dutch adults
Eye movement perimetry (EMP) expresses the decline in visual field (VF) responsiveness based on the deviation in saccadic reaction times (SRTs) from their expected age-similar responses (normative database). S...
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Article
Blindness in glaucoma: primary open-angle glaucoma versus primary angle-closure glaucoma—a meta-analysis
To estimate the risk of blindness with primary angle-closure glaucoma (PACG) compared to primary open-angle glaucoma (POAG) in those population-based studies that reported blindness rates for both PACG and POAG.
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Article
Analysis of retracted articles in the ophthalmic literature
To evaluate the frequency and reason for retraction of ophthalmology publications.
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Article
Open AccessA haploscope based binocular pupillometer system to quantify the dynamics of direct and consensual Pupillary Light Reflex
This study described the development of a haploscope-based pupillometer for the parametrization of the Pupillary Light Reflex (PLR), and its feasibility in a set of 30 healthy subjects (light or dark-colored i...
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Article
Open AccessSaccadic reaction time in mirror image sectors across horizontal meridian in eye movement perimetry
In eye movement perimetry (EMP), the saccadic reaction time (SRT) to ‘seen’ visual stimuli are delayed in glaucoma. Evaluating SRT behaviour in hemi-field sectors could refine its clinical implication. The dev...
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Chapter
Glaucoma: Burden, Practices, and Challenges
Glaucoma is a neurodegenerative disorder characterized by typical degenerative structural changes of the retinal ganglion cells in the optic nerve head and produces corresponding visual field defects [1]. The ...
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Article
Eye Movement Perimetry and Frequency Doubling Perimetry: clinical performance and patient preference during glaucoma screening
To evaluate the screening accuracy of an Eye Movement Perimetry (EMP) in comparison with Frequency Doubling Perimetry (FDP) and to investigate the patient preference and perception towards these visual field s...
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Article
Prospective analysis of the predictors of glaucoma following surgery for congenital and infantile cataract
A prospective longitudinal cohort study was performed to assess the incidence of and risk factors for the development of glaucoma following surgery for congenital/infantile cataract.
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Chapter
Quantitative Trait for Glaucoma
Dissecting the genetic architecture of complex or multifactorial disorders always demanded different strategies in addition to the classical gene map** methods, due to the high level of clinical and genetic ...
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Article
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci
Chiea Chuen Khor, Tin Aung, Francesca Pasutto, Janey Wiggs and colleagues report a global genome-wide association study of exfoliation syndrome and a fine-map** analysis of a previously identified disease-as...
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Article
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma
Chiea Chuen Khor, Tin Aung and colleagues report the results of a large genome-wide association study of primary angle closure glaucoma. They identify five new susceptibility loci and provide insights into dis...
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Article
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma
Ningli Wang, Tin Aung and colleagues report genome-wide association analyses for primary angle closure glaucoma, a major cause of blindness worldwide. They identify three loci newly associated with this disease.
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Article
Transforming Growth Factor β-1 −509C>T Polymorphism in Indian Patients with Primary Open Angle Glaucoma
Background: Extracellular matrix (ECM) accumulation in the trabecular meshwork tissues of glaucoma patients has been demonstrated as one of the factors that contribute to glaucoma pathology. Tran...