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  1. No Access

    Article

    Hair and Serum Trace Element and Mineral Levels Profiles in Women with Premenopausal and Postmenopausal Osteoporosis

    The objective of the present study was to evaluate serum and hair trace element and mineral levels in women with osteoporosis, as well as to estimate the impact of menopausal status on the profile of trace ele...

    Anatoly V. Skalny, Tatiana V. Korobeinikova… in Biological Trace Element Research (2023)

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    Article

    The role of hypoxia-inducible factor 1 alpha (HIF-1α) modulation in heavy metal toxicity

    Hypoxia-inducible factor 1 (HIF-1) is an oxygen-sensing transcriptional regulator orchestrating a complex of adaptive cellular responses to hypoxia. Several studies have demonstrated that toxic metal exposure ...

    Michael Aschner, Anatoly V. Skalny, Rongzhu Lu, Abel Santamaria… in Archives of Toxicology (2023)

  3. No Access

    Article

    Ferroptosis as a mechanism of non-ferrous metal toxicity

    Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron metabolism and induction ...

    Michael Aschner, Anatoly V. Skalny, Airton C. Martins… in Archives of Toxicology (2022)

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    Article

    The Role of Human LRRK2 in Methylmercury-Induced Inhibition of Microvesicle Formation of Cephalic Neurons in Caenorhabditis elegans

    In a previous study, we have shown that methylmercury (MeHg) exposure causes focal aggregation of intracellular transgenic mCherry protein in dendrites of cephalic (CEP) neurons in Caenorhabditis elegans (C. eleg...

    Tao Ke, Abel Santamaria, Joao B. T. Rocha, Alexey A. Tinkov… in Neurotoxicity Research (2020)

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    Article

    Activation of autophagic flux and the Nrf2/ARE signaling pathway by hydrogen sulfide protects against acrylonitrile-induced neurotoxicity in primary rat astrocytes

    Hydrogen sulfide (H2S), the third gasotransmitter, has been shown to act as a neuroprotective factor in numerous pathological processes; however, its underlying mechanism(s) of action remain unclear. It is widely...

    Bobo Yang, Yu Bai, Changsheng Yin, Hai Qian, Guangwei **ng… in Archives of Toxicology (2018)