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Article
Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update
Drug-induced liver injury (DILI) is an important adverse drug reaction that can lead to acute liver failure or even death in severe cases. Currently, the diagnosis of DILI still follows the strategy of exclusi...
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Article
Clinic-radiomics model using liver magnetic resonance imaging helps predict chronicity of drug-induced liver injury
Some drug-induced liver injury (DILI) cases may become chronic, even after drug withdrawal. Radiomics can predict liver disease progression. We established and validated a predictive model incorporating the cl...
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Article
Neutralizing monoclonal antibodies present new prospects to treat SARS-CoV-2 infections
The coronavirus disease 2019 (COVID-19) has caused global public health and economic crises. Thus, new therapeutic strategies and effective vaccines are urgently needed to cope with this severe pandemic. The d...
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Article
Laboratory-based Surveillance and Clinical Profile of Sporadic HEV Infection in Shanghai, China
The study aimed to describe the epidemiological, virological and clinical features of sporadic HEV infection in eastern China. A total of 6112 patient sera were tested for anti-HEV IgG or anti-HEV IgM during o...
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Article
Open AccessSUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in hepatocytes. The role of SENP3 in lipid metabolism, particularly NAFLD, is unclear. Our results showed that hepatic...
