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    Article

    Effects of transgenic overexpression of diapause hormone and diapause hormone receptor genes on non-diapause silkworm

    Diapause is a state of developmental arrest that is most often observed in arthropods, especially insects. The domesticated silkworm, Bombyx mori, is a typical insect that enters diapause at an early embryonic st...

    Chunying Gong, Wenhui Zeng, Tianyang Zhang, Rongpeng Liu, Yao Ou in Transgenic Research (2017)

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    Article

    Insights into the regulatory characteristics of silkworm fibroin gene promoters using a modified Gal4/UAS system

    The silkworm Bombyx mori is a valuable insect that synthesizes bulk amounts of fibroin protein in its posterior silk gland (PSG) and weaves these proteins into silk cocoons. The mechanism by which the fibroin pro...

    Rongpeng Liu, Wenhui Zeng, Tingting Tan, Tao Chen, Qin Luo, Dawei Qu in Transgenic Research (2019)

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    Article

    Expression and characterization of recombinant human VEGF165 in the middle silk gland of transgenic silkworms

    Recombinant human vascular endothelial growth factor (rhVEGF) has important applications in therapeutic angiogenesis and inhibition of VEGF-mediated pathological angiogenesis. Previous studies have shown that ...

    Tianyang Zhang, Rongpeng Liu, Qin Luo, Dawei Qu, Tao Chen, Ou Yao in Transgenic Research (2019)

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    Article

    The intronic promoter of Actin4 mediates high-level transgene expression mainly in the wing and epidermis of silkworms

    The cytoplasmic actin gene Actin4 (A4) in silkworm (Bombyx mori) was isolated 20 years ago and has a distal promoter upstream of the first exon and a proximal promoter within the first intron; however, how the pr...

    Tingting Tan, Rongpeng Liu, Qin Luo, **gwen Ma, Yao Ou, Wenhui Zeng in Transgenic Research (2020)

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    Article

    A transcriptome atlas of silkworm silk glands revealed by PacBio single-molecule long-read sequencing

    The silk gland of the silkworm Bombyx mori is a specialized organ where silk proteins are efficiently synthesized under precise regulation that largely determines the properties of silk fibers. To understand the ...

    Tao Chen, Qiwei Sun, Yan Ma, Wenhui Zeng, Rongpeng Liu in Molecular Genetics and Genomics (2020)