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Article
A transcriptome atlas of silkworm silk glands revealed by PacBio single-molecule long-read sequencing
The silk gland of the silkworm Bombyx mori is a specialized organ where silk proteins are efficiently synthesized under precise regulation that largely determines the properties of silk fibers. To understand the ...
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Article
The intronic promoter of Actin4 mediates high-level transgene expression mainly in the wing and epidermis of silkworms
The cytoplasmic actin gene Actin4 (A4) in silkworm (Bombyx mori) was isolated 20 years ago and has a distal promoter upstream of the first exon and a proximal promoter within the first intron; however, how the pr...
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Article
Insights into the regulatory characteristics of silkworm fibroin gene promoters using a modified Gal4/UAS system
The silkworm Bombyx mori is a valuable insect that synthesizes bulk amounts of fibroin protein in its posterior silk gland (PSG) and weaves these proteins into silk cocoons. The mechanism by which the fibroin pro...
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Article
Expression and characterization of recombinant human VEGF165 in the middle silk gland of transgenic silkworms
Recombinant human vascular endothelial growth factor (rhVEGF) has important applications in therapeutic angiogenesis and inhibition of VEGF-mediated pathological angiogenesis. Previous studies have shown that ...
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Article
Effects of transgenic overexpression of diapause hormone and diapause hormone receptor genes on non-diapause silkworm
Diapause is a state of developmental arrest that is most often observed in arthropods, especially insects. The domesticated silkworm, Bombyx mori, is a typical insect that enters diapause at an early embryonic st...