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Article
Cuproptosis in lung cancer: therapeutic options and prognostic models
Lung cancer (LC) is a serious threat to mankind. The survival of LC patients is still poor despite the enormous efforts that have been made to develop novel treatments. A copper-dependent cell death termed cup...
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Article
Replication study and meta-analysis indicate a suggestive association of RUNX3 locus with primary biliary cholangitis
Susceptibility to primary biliary cholangitis (PBC) is in part genetically determined. In our previous PBC genome-wide association study (GWAS) in 1118 Han Chinese PBC and 4036 controls, we noted that multiple...
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Article
Open AccessA genome-wide association study identifies six novel risk loci for primary biliary cholangitis
Primary biliary cholangitis (PBC) is an autoimmune liver disease with a strong hereditary component. Here, we report a genome-wide association study that included 1,122 PBC cases and 4,036 controls of Han Chin...
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Article
Multiple Genetic Variants Associated with Primary Biliary Cirrhosis in a Han Chinese Population
Multiple genome-wide association studies of primary biliary cirrhosis (PBC) in both European and Japanese ancestries have shown significant associations of many genetic loci contributing to the susceptibility ...