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Article
Open AccessContinuing the sequence? Towards an economic evaluation of whole genome sequencing for the diagnosis of rare diseases in Scotland
Novel developments in genomic medicine may reduce the length of the diagnostic odyssey for patients with rare diseases. Health providers must thus decide whether to offer genome sequencing for the diagnosis of...
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Discrete Choice Experiments
Discrete choice experiments (DCEs) were introduced into health economics in the early 1990s to ensure a person-centred approach to economic evaluation. While economic evaluation had focused on clinical outcome...
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Article
Open AccessComparative study of new imaging technologies for the diagnosis of glaucoma: design and conduct of a multi-centre diagnostic accuracy study
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Article
Fast replenishment of initial carbon stores after defoliation by the pine processionary moth and its relationship to the re-growth ability of trees
Defoliation by herbivores may alter the source:sink balance of trees leading to transient decreases in carbon (C) stores. When C stores are replenished concurrently with re-growth both processes may compete, s...
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Article
Open AccessA pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery - the FOCCUS study
Fluid strategies may impact on patient outcomes in major elective surgery. We aimed to study the effectiveness and cost-effectiveness of pre-operative fluid loading in high-risk surgical patients undergoing ma...
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Article
Open AccessAntitumor activity against murine lymphoma L5178Y model of proteins from cacao (Theobroma cacao L.) seeds in relation with in vitro antioxidant activity
Recently, proteins and peptides have become an added value to foodstuffs due to new knowledge about its structural analyses as related to antioxidant and anticancer activity. Our goal was to evaluate if protei...
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Article
Analogs of sex pheromone of processionary moth,Thaumetopoea pityocampa: Synthesis and biological activity
The synthesis and biological activity of some analogs of (Z)-13-hexadecen-11-ynyl acetate1, the major component of the sex pheromone of the processionary mothThaumetopoea pityocampa is described. The analogs have...