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    Targeting mammalian organelles with internalizing phage (iPhage) libraries

    Techniques that are largely used for protein interaction studies and the discovery of intracellular receptors, such as affinity-capture complex purification and the yeast two-hybrid system, may produce inaccur...

    Roberto Rangel, Andrey S Dobroff, Liliana Guzman-Rojas in Nature Protocols (2013)

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    Design and construction of targeted AAVP vectors for mammalian cell transduction

    Bacteriophage (phage) evolved as bacterial viruses, but can be adapted to transduce mammalian cells through ligand-directed targeting to a specific receptor. We have recently reported a new generation of hybri...

    Amin Hajitou, Roberto Rangel, Martin Trepel, Suren Soghomonyan in Nature Protocols (2007)

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    Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU

    Non-invasive imaging of transgene expression requires the appropriate combination of a reporter gene and a reporter probe. [18F]FEAU positron emission tomography (PET) is used for the assessment of herpes simplex...

    Suren Soghomonyan, Amin Hajitou, Roberto Rangel, Martin Trepel in Nature Protocols (2007)