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Article
Targeting mammalian organelles with internalizing phage (iPhage) libraries
Techniques that are largely used for protein interaction studies and the discovery of intracellular receptors, such as affinity-capture complex purification and the yeast two-hybrid system, may produce inaccur...
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Article
Design and construction of targeted AAVP vectors for mammalian cell transduction
Bacteriophage (phage) evolved as bacterial viruses, but can be adapted to transduce mammalian cells through ligand-directed targeting to a specific receptor. We have recently reported a new generation of hybri...
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Article
Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU
Non-invasive imaging of transgene expression requires the appropriate combination of a reporter gene and a reporter probe. [18F]FEAU positron emission tomography (PET) is used for the assessment of herpes simplex...