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Article
Pulmonary lesion after surgery for renal cancer: progression or new primary?
To investigate clinical and radiological differences between kidney metastases to the lung (RCCM +) and metachronous lung cancer (LC) detected during follow-up in patients surgically treated for Renal Cell Car...
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Article
Open AccessIntegrative multi-region molecular profiling of primary prostate cancer in men with synchronous lymph node metastasis
Localized prostate cancer is frequently composed of multiple spatially distinct tumors with significant inter- and intra-tumoral molecular heterogeneity. This genomic diversity gives rise to many competing clo...
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Article
Open AccessProgressive alteration of murine bladder elasticity in actinic cystitis detected by Brillouin microscopy
Bladder mechanical properties are critical for organ function and tissue homeostasis. Therefore, alterations of tissue mechanics are linked to disease onset and progression. This study aims to characterize the...
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Article
SIUrO best practice recommendations to optimize BRCA 1/2 gene testing from DNA extracted from bone biopsy in mCRPC patients (BRCA Optimal Bone Biopsy Procedure: BOP)
The main guidelines and recommendations for the implementation of the BRCA1/2 somatic test do not focus on the clinical application of predictive testing on bone metastases, a frequent condition in metastatic pro...
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Article
Open AccessA simple and robust nanosystem for photoacoustic imaging of bladder cancer based on α5β1-targeted gold nanorods
Early detection and removal of bladder cancer in patients is crucial to prevent tumor recurrence and progression. Because current imaging techniques may fail to detect small lesions of in situ carcinomas, pati...
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Article
Pancreatic metastases after surgery for renal cell carcinoma: survival and pathways of progression
Metastatic ccRCC has peculiar tropism in the pancreas. We describe the characteristics and pathways of progression of patients with PM in a large multi-institutional consortium and compare them to patients wit...
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Chapter
Pathologic Features of Response to Neoadjuvant Therapies in Muscle-Invasive Bladder Cancer: More than Meets the Eye
The tumor microenvironment represents the arena where pro- and antitumor forces collide. As in every battlefield, signs of the fight can be recognized by an expert eye, like the eye of the pathologist. In addi...
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Article
Correction to: Renal histology across the stages of chronic kidney disease
A correction to this paper has been published: https://doi.org/10.1007/s40620-021-01059-1
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Article
Renal histology across the stages of chronic kidney disease
The chronic kidney disease (CKD) classification represents a simple tool to evaluate kidney disease. However, it is not based on kidney histology and this might limit the correlation between renal function and...
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Article
The role of 18F-FAZA PET/CT in detecting lymph node metastases in renal cell carcinoma patients: a prospective pilot trial
The accurate detection of nodal invasion is an unmet need in the clinical staging of renal cancer. Positron emission tomography (PET) with 18F-fluoroazomycin arabinoside (18F-FAZA), a hypoxia specific tracer, ...
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Article
IL-23 secreted by myeloid cells drives castration-resistant prostate cancer
Patients with prostate cancer frequently show resistance to androgen-deprivation therapy, a condition known as castration-resistant prostate cancer (CRPC). Acquiring a better understanding of the mechanisms th...
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Article
Open AccessBladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism
The inhibitory effects demonstrated by activation of cannabinoid receptors (CB) on cancer proliferation and migration may also play critical roles in controlling bladder cancer (BC). CB expression on human nor...
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Article
Open AccessLinearized texture of three-dimensional extracellular matrix is mandatory for bladder cancer cell invasion
In the fields of biomaterials and tissue engineering simulating the native microenvironment is of utmost importance. As a major component of the microenvironment, the extracellular matrix (ECM) contributes to ...
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Article
Open AccessUsefulness of pT1 substaging in papillary urothelial bladder carcinoma
When treating bladder cancer patients, the most significant problems usually concern cases with high-grade non-muscle-invasive carcinoma, and a better understanding of which patients would benefit from early r...
