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Open AccessDengue virus-pandemic influenza virus co-infection results in enhanced influenza virus replication through inhibition of apoptosis
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Open AccessSingle injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease
Nipah virus (NiV) is a highly pathogenic zoonotic agent in the family Paramyxoviridae that is maintained in nature by bats. Outbreaks have occurred in Malaysia, Singapore, India, and Bangladesh and have been asso...
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Open AccessIntranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase
We recently reported the development of the first African green monkey (AGM) model for COVID-19 based on a combined liquid intranasal (i.n.) and intratracheal (i.t.) exposure to severe acute respiratory syndro...
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Open AccessA single dose investigational subunit vaccine for human use against Nipah virus and Hendra virus
Nipah and Hendra viruses are highly pathogenic bat-borne paramyxoviruses recently included in the WHO Blueprint priority diseases list. A fully registered horse anti-Hendra virus subunit vaccine has been in us...
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Open AccessSingle dose rVSVΔG-JUNVGP vaccine protects guinea pigs against lethal Junin virus challenge
Junin virus (JUNV) is a pathogen of biodefense importance due to its potential for aerosol transmission and mortality rates reaching 30%. Currently, there are no JUNV vaccines licensed by the United States Foo...