-
Article
Open AccessComparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality
Process development for transferring lab-scale research workflows to automated manufacturing procedures is critical for chimeric antigen receptor (CAR)-T cell therapies. Therefore, the key factor for cell viab...
-
Article
Determination of G-protein–coupled receptor oligomerization by molecular brightness analyses in single cells
Oligomerization of membrane proteins has received intense research interest because of their importance in cellular signaling and the large pharmacological and clinical potential this offers. Fluorescence imag...
-
Chapter
On Invariant Within Equivalence Coordinate System (IWECS) Transformations
In exploratory data analysis and data mining in the very common setting of a data set \(\mathbb{X}\) of vectors from
-
Reference Work Entry In depth
Asymptotic Relative Efficiency in Estimation
-
Chapter and Conference Paper
A Depth Function and a Scale Curve Based on Spatial Quantiles
Spatial quantiles, based on the L 1 norm in a certain sense, provide an appealing vector extension of univariate quantiles and generate a useful “volume” functional based on spatial “central regio...
-
Article
Robust Estimation of Tail Parameters for Two-Parameter Pareto and Exponential Models via Generalized Quantile Statistics
Robust estimation of tail index parameters is treated for (equivalent) two-parameter Pareto and exponential models. These distributions arise as parametric models in actuarial science, economics, telecommunica...