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  1. Article

    Open Access

    Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality

    Process development for transferring lab-scale research workflows to automated manufacturing procedures is critical for chimeric antigen receptor (CAR)-T cell therapies. Therefore, the key factor for cell viab...

    Nadine von Auw, Robert Serfling, Reni Kitte, Nadja Hilger in Scientific Reports (2023)

  2. No Access

    Article

    Determination of G-protein–coupled receptor oligomerization by molecular brightness analyses in single cells

    Oligomerization of membrane proteins has received intense research interest because of their importance in cellular signaling and the large pharmacological and clinical potential this offers. Fluorescence imag...

    Ali Işbilir, Robert Serfling, Jan Möller, Romy Thomas, Chiara De Faveri in Nature Protocols (2021)

  3. No Access

    Chapter

    On Invariant Within Equivalence Coordinate System (IWECS) Transformations

    In exploratory data analysis and data mining in the very common setting of a data set \(\mathbb{X}\) of vectors from

    Robert Serfling in Modern Nonparametric, Robust and Multivariate Methods (2015)

  4. No Access

    Reference Work Entry In depth

    Asymptotic Relative Efficiency in Estimation

    Robert Serfling in International Encyclopedia of Statistical Science (2011)

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    Chapter and Conference Paper

    A Depth Function and a Scale Curve Based on Spatial Quantiles

    Spatial quantiles, based on the L 1 norm in a certain sense, provide an appealing vector extension of univariate quantiles and generate a useful “volume” functional based on spatial “central regio...

    Robert Serfling in Statistical Data Analysis Based on the L1-Norm and Related Methods (2002)

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    Article

    Robust Estimation of Tail Parameters for Two-Parameter Pareto and Exponential Models via Generalized Quantile Statistics

    Robust estimation of tail index parameters is treated for (equivalent) two-parameter Pareto and exponential models. These distributions arise as parametric models in actuarial science, economics, telecommunica...

    Vytaras Brazauskas, Robert Serfling in Extremes (2000)