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Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity

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  1. Article

    Open Access

    Author Correction: Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial

    Matthew D. Galsky, Siamak Daneshmand, Sudeh Izadmehr… in Nature Medicine (2024)

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  2. Article

    Open Access

    Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial

    Cystectomy is a standard treatment for muscle-invasive bladder cancer (MIBC), but it is life-altering. We initiated a phase 2 study in which patients with MIBC received four cycles of gemcitabine, cisplatin, p...

    Matthew D. Galsky, Siamak Daneshmand, Sudeh Izadmehr… in Nature Medicine (2023)

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  3. Article

    Open Access

    Dissecting microsatellite instability in colorectal cancer: one size does not fit all

    Microsatellite instability (MSI) marks distinct subsets of tumors in many cancer types and is caused by mutations in genes required for mismatch repair. A recent report analyses the molecular foundations of MS...

    Robert M. Samstein, Timothy A. Chan in Genome Medicine (2017)

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