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  1. No Access

    Article

    Functional Equivariance and Conservation Laws in Numerical Integration

    Preservation of linear and quadratic invariants by numerical integrators has been well studied. However, many systems have linear or quadratic observables that are not invariant, but which satisfy evolution eq...

    Robert I. McLachlan, Ari Stern in Foundations of Computational Mathematics (2024)

  2. No Access

    Article

    Frequency, morbidity and equity — the case for increased research on male fertility

    Currently, most men with infertility cannot be given an aetiology, which reflects a lack of knowledge around gamete production and how it is affected by genetics and the environment. A failure to recognize the...

    Sarah Kimmins, Richard A. Anderson, Christopher L. R. Barratt in Nature Reviews Urology (2024)

  3. Article

    Open Access

    Diverse monogenic subforms of human spermatogenic failure

    Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically incurable. Defining the genetic basis of NOA has proven challenging, and the most advanced classification of NOA subf...

    Liina Nagirnaja, Alexandra M. Lopes, Wu-Lin Charng, Brian Miller in Nature Communications (2022)

  4. No Access

    Article

    Analysing ‘Simple’ Image Registrations

    Processes such as growth and atrophy cause changes through time that can be visible in a series of medical images, following the hypothesis that form follows function. As was hypothesised by D’Arcy Thompson mo...

    Stephen Marsland, Robert I. McLachlan in Journal of Mathematical Imaging and Vision (2021)

  5. No Access

    Article

    Preservation of Bifurcations of Hamiltonian Boundary Value Problems Under Discretisation

    We show that symplectic integrators preserve bifurcations of Hamiltonian boundary value problems and that non-symplectic integrators do not. We provide a universal description of the breaking of umbilic bifurc...

    Robert I McLachlan, Christian Offen in Foundations of Computational Mathematics (2020)

  6. No Access

    Article

    Parallelization, initialization, and boundary treatments for the diamond scheme

    We study a class of general purpose linear multisymplectic integrators for Hamiltonian wave equations based on a diamond-shaped mesh. On each diamond, the PDE is discretized by a symplectic Runge–Kutta method....

    Stephen Marsland, Robert I. McLachlan, Matthew C. Wilkins in Numerical Algorithms (2020)

  7. No Access

    Article

    Multisymplecticity of Hybridizable Discontinuous Galerkin Methods

    In this paper, we prove necessary and sufficient conditions for a hybridizable discontinuous Galerkin method to satisfy a multisymplectic conservation law, when applied to a canonical Hamiltonian system of par...

    Robert I. McLachlan, Ari Stern in Foundations of Computational Mathematics (2020)

  8. No Access

    Article

    Currents and Finite Elements as Tools for Shape Space

    The nonlinear spaces of shapes (unparameterized immersed curves or submanifolds) are of interest for many applications in image analysis, such as the identification of shapes that are similar modulo the action...

    James Benn, Stephen Marsland in Journal of Mathematical Imaging and Vision (2019)

  9. No Access

    Article

    Symplectic integration of boundary value problems

    Symplectic integrators can be excellent for Hamiltonian initial value problems. Reasons for this include their preservation of invariant sets like tori, good energy behaviour, nonexistence of attractors, and g...

    Robert I. McLachlan, Christian Offen in Numerical Algorithms (2019)

  10. Article

    Open Access

    Cryopreservation of reproductive material before cancer treatment: a qualitative study of health care professionals’ views about ways to enhance clinical care

    Cancer treatment can diminish fertility in women and men. The need for fertility preservation is growing as increasing numbers of people survive cancer. Cryostorage of reproductive material to preserve potenti...

    Karin Hammarberg, Maggie Kirkman, Catharyn Stern in BMC Health Services Research (2017)

  11. No Access

    Article

    Geometry of Discrete-Time Spin Systems

    Classical Hamiltonian spin systems are continuous dynamical systems on the symplectic phase space \((S^2)^n\) ...

    Robert I. McLachlan, Klas Modin, Olivier Verdier in Journal of Nonlinear Science (2016)

  12. No Access

    Article

    B-series methods are exactly the affine equivariant methods

    Butcher series, also called B-series, are a type of expansion, fundamental in the analysis of numerical integration. Numerical methods that can be expanded in B-series are defined in all dimensions, so they co...

    Robert I. McLachlan, Klas Modin, Hans Munthe-Kaas, Olivier Verdier in Numerische Mathematik (2016)

  13. No Access

    Reference Work Entry In depth

    Composition Methods

    Robert I. McLachlan in Encyclopedia of Applied and Computational Mathematics (2015)

  14. No Access

    Article

    Geometric Generalisations of shake and rattle

    A geometric analysis of the shake and rattle methods for constrained Hamiltonian problems is carried out. The study reveals the underlying differential geometric foundation of the two methods, and the exact relat...

    Robert I McLachlan, Klas Modin, Olivier Verdier in Foundations of Computational Mathematics (2014)

  15. No Access

    Article

    Geodesic Warps by Conformal Map**s

    In recent years there has been considerable interest in methods for diffeomorphic war** of images, with applications in e.g. medical imaging and evolutionary biology. The original work generally cited is tha...

    Stephen Marsland, Robert I. McLachlan in International Journal of Computer Vision (2013)

  16. No Access

    Article

    Energy-Preserving Integrators and the Structure of B-series

    B-series are a powerful tool in the analysis of Runge–Kutta numerical integrators and some of their generalizations (“B-series methods”). A general goal is to understand what structure-preservation can be achi...

    Elena Celledoni, Robert I. McLachlan in Foundations of Computational Mathematics (2010)

  17. No Access

    Article

    Preservation and destruction of periodic orbits by symplectic integrators

    We investigate what happens to periodic orbits and lower-dimensional tori of Hamiltonian systems under discretisation by a symplectic one-step method where the system may have more than one degree of freedom. ...

    Robert I. McLachlan, Dion R. J. O’Neale in Numerical Algorithms (2010)

  18. Article

    Open Access

    Determinants of male reproductive health disorders: the Men in Australia Telephone Survey (MATeS)

    The relationship between reproductive health disorders and lifestyle factors in middle-aged and older men is not clear. The aim of this study is to describe lifestyle and biomedical associations as possible ca...

    Carol A Holden, Robert I McLachlan, Marian Pitts, Robert Cumming in BMC Public Health (2010)

  19. No Access

    Article

    Hypogonadotropism with elevated serum testosterone: reversible causes of secondary infertility

    Background A 33-year-old man presented with secondary infertility, increased libido, and extreme oligospermia. Testicular volumes were reduced, but no gynecomastia was apparent and androgen abuse was denied.

    Robert I McLachlan, David M de Kretser in Nature Clinical Practice Urology (2006)

  20. No Access

    Article

    The Discrete Moser–Veselov Algorithm for the Free Rigid Body, Revisited

    In this paper we revisit the Moser–Veselov description of the free rigid body in body coordinates, which, in the 3 × 3 case, can be implemented as an explicit, second-order, integrable approximation of...

    Robert I. McLachlan, Antonella Zanna in Foundations of Computational Mathematics (2005)

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