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  1. Article

    Open Access

    Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations

    The in vitro pharmacology of baricitinib, upadacitinib, and tofacitinib was evaluated to understand differences among these JAK inhibitors (JAKis) at the cellular level.

    Iain B. McInnes, Nicole L. Byers, Richard E. Higgs… in Arthritis Research & Therapy (2019)

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  2. Article

    Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation

    Cytokines play a critical role in the normal development and function of the immune system. On the other hand, many rheumatologic diseases are characterized by poorly controlled responses to or dysregulated pr...

    Robert A Ortmann, Tammy Cheng, Roberta Visconti… in Arthritis Research & Therapy (1999)

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