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  1. No Access

    Article

    Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial

    Adeno-associated viral vector-mediated transfer of DNA coding for broadly neutralizing anti-HIV antibodies (bnAbs) offers an alternative to attempting to induce protection by vaccination or by repeated infusio...

    Joseph P. Casazza, Evan M. Cale, Sandeep Narpala, Galina V. Yamshchikov… in Nature Medicine (2022)

  2. Article

    Open Access

    An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial

    A novel avian influenza subtype, A/H7N9, emerged in 2013 and represents a public health threat with pandemic potential. We have previously shown that DNA vaccine priming increases the magnitude and quality of ...

    Adam D. DeZure, Emily E. Coates, Zonghui Hu, Galina V. Yamshchikov… in npj Vaccines (2017)

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  3. Article

    Open Access

    Development of a mammalian cell culture process for rapid Clinical-Scale production of novel Influenza Nanoparticle vaccines

    Payal Biswas, Christian Trozado, James Lee, Richard M Schwartz in BMC Proceedings (2015)

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  4. Article

    Open Access

    CHO-DHFR cell line development platform: Application of Clonepix and Automated Mini Bioreactor (AMBR) technologies to meet accelerated timelines

    Venkata R Mangalampalli, Dyane Wycuff, Mingzhong Chen, David Berlinger… in BMC Proceedings (2015)

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  5. No Access

    Article

    A serum-free Vero production platform for a chimeric virus vaccine candidate

    MedImmune Vaccines has engineered a live, attenuated chimeric virus that could prevent infections caused by parainfluenza virus type 3 (PIV3) and respiratory syncytial virus (RSV), causative agents of acute re...

    Inn H. Yuk, Gina B. Lin, Hui Ju, Inesse Sifi, Yvonne Lam, Armida Cortez… in Cytotechnology (2006)

  6. No Access

    Article

    Expansion of Human Bone Marrow Progenitor Cells in a High Cell Density Continuous Perfusion System

    We describe here a continuous perfusion bioreactor system that enables a population of unselected human mononuclear bone marrow cells obtained from adult donors to expand up to 20 to 25-fold over a two-week pe...

    Bernhard O. Palsson, Se-Hwan Paek, Richard M. Schwartz, Mahshid Palsson… in Bio/Technology (1993)

  7. No Access

    Article

    The influence of extra-cellular matrix and stroma remodeling on the productivity of long-term human bone marrow cultures

    The stromal cell layer is believed to play an important role in long-term human bone marrow cultures (LTHBMCs). At present, neither the role that the stromal cell extra-cellular matrix (ECM) plays in influenci...

    Richard M. Schwartz, Jerry Caldwell, Michael F. Clarke… in Cytotechnology (1992)

  8. No Access

    Chapter and Conference Paper

    Acoustic-Phonetic Decoding of Speech

    Several methods for acoustic-phonetic decoding are reviewed. Emphasis is placed on the need for mathematical methods for speech recognition. Several examples of statistical methods are described. The author pr...

    Richard M. Schwartz, Y. Chow, M. Dunham… in Recent Advances in Speech Understanding an… (1988)