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Article
Open AccessInterleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
Neuroinflammation, typified by elevated levels of interleukin-1 (IL-1) α and β, and deficits in proteostasis, characterized by accumulation of polyubiquitinated proteins and other aggregates, are associated wi...
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Chapter
Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands
The synthesis, crystal structures, and photophysical properties of twenty-three 4f and d-4f clusters based on eight salen-type Schiff base ligands are described in this chapter. Most of these lanthanide-based ...
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Chapter
MR Urography in Children
Magnetic resonance urography (MRU) is a powerful clinical tool that fuses anatomic information with functional data in a single test without the use of ionizing radiation. This chapter provides an overview of ...
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Article
The role of TG2 in ECV304-related vasculogenic mimicry
Tumour vasculogenesis can occur by a process referred to as vasculogenic mimicry, whereby the vascular structures are derived from the tumour itself. These tumours are highly aggressive and do not respond well...
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Article
Drop metastases to the pediatric spine revealed with diffusion-weighted MR imaging
Identifying drop metastases to the spine from pediatric brain tumors is crucial to treatment and prognosis. MRI is currently the gold standard for identifying drop metastases, more sensitive than CSF cytology,...
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Article
Open AccessApolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors
We have previously outlined functional interactions, including feedback cycles, between several of the gene products implicated in the pathogenesis of Alzheimer's disease. A number of Alzheimer-related stresso...
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Article
Bilateral congenital midureteric strictures associated with multicystic dysplastic kidney and hydronephrosis: evaluation with MR urography
We report a case of bilateral congenital midureteric strictures diagnosed using MR urography. The severity of obstruction differed in the two ureters, resulting in a multicystic dysplastic kidney (MCDK) with a...
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Article
Synthesis and Crystal Structure of a New Heterotrinuclear Schiff-Base Zn–Gd Complex
A heterotrinuclear Zn–Gd complex [GdZn2L2(OAc)2](CF3SO3) (1) based on the salphen Schiff-base ligand bis(3-methoxysalicylidene)-1,2-phenylenediamine (H2L) was synthesized and characterized by single crystal X-ray...
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Article
Molecular cloning and regulation of mRNA expression of the thyrotropin β and glycoprotein hormone α subunits in red drum, Sciaenops ocellatus
Full-length cDNAs for thyrotropin β (TSHβ) and glycoprotein hormone α (GSUα) subunits were cloned and sequenced from the red drum (Sciaenops ocellatus). The cDNAs for TSHβ (877 bp) and GSUα (661 bp) yielded predi...
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Article
MRU post-processing
Dynamic magnetic resonance urography (MRU) scans acquired in conjunction with an injection of a contrast agent can be used to estimate a number of parameters that reflect renal function. This article discusses...
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Article
MR urography evaluation of obstructive uropathy
Hydronephrosis and the evaluation of obstructive uropathy are the most common indications for MR urography in our practice. Typically our patients fall into one of two groups: infants with antenatal hydronephr...
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Article
MR urography in children: how we do it
In this article we introduce the topic of MR urography in children, focusing on the details required to obtain consistently high-quality scans. Much of the information presented is based on our experience duri...
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Article
Evaluation of UPJ obstruction before and after pyeloplasty using MR urography
This article builds on the previous article in this symposium and shows how MR urography contributes to the postoperative evaluation of children with UPJ obstruction. By analyzing the postoperative results, we...
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Article
Evaluation of reflux nephropathy, pyelonephritis and renal dysplasia
MR urography has the potential to significantly improve our understanding of the relationship between reflux nephropathy, pyelonephritis, vesicoureteric reflux and renal dysplasia. MR urography utilizes multip...
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Article
Chemical Routes to Ultra Thin Films for Copper Barriers and Liners
Triruthenium dodecarbonyl and trimethylphosphine or triphenylphosphine, and cis-ruthenium(II)dihydridotetrakis-(trimethylphophine) were used in flowing hydrogen or argon at 575 K to explore the effect of chang...
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Article
MR urography in children
MR urography represents the next step in the evolution of uroradiology in children by combining superb anatomic imaging with quantitative functional evaluation in a single examination that does not use ionizin...
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Article
Synthesis and crystal structure of (η5-C5H5)2Ti(NH(2,4-(C \({\equiv}\) CSiMe3)2C6H3))2
The crystal structure of the bis-amido complex of Ti(IV) (η5-C5H5)2Ti(NH(2,4-(C \({\equiv}\) CSiMe3)2C6H3))2 is reporte...
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Article
Age dependence of the renal apparent diffusion coefficient in children
Diffusion imaging has proved to be a powerful tool for diagnosing ischemic lesions in the brain, and the technique is now being applied to other organs, including the kidneys. For quantitative studies it is im...
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Article
MR imaging of kidneys: functional evaluation using F-15 perfusion imaging
Children with hydronephrosis are typically investigated by a combination of diuretic renal scintigraphy, ultrasound, and voiding cystourethrography. Unfortunately, there is no gold standard to assess obstruction.
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Article
Relationship between function and perfusion early after acute myocardial infarction
To assess the relationship between baseline left ventricle function, functional reserve and resting myocardial perfusion in patients with acute myocardial infarction (AMI). After AMI the presence of dysfunctio...
