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Article
In silico and network pharmacology analysis of fucosterol: a potent anticancer bioactive compound against HCC
The Fucaceae family of marine brown algae includes Ascophyllum nodosum. Fucosterol (FSL) is a unique bioactive component that was identified through GC-MS analysis of the hydroalcoholic extract of A. nodosum. Fuc...
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Article
Recent insights on pharmacological potential of lycopene and its nanoformulations: an emerging paradigm towards improvement of human health
Nutritional antioxidants derived from phytochemicals have been shown to have multifaceted health benefits via the pleiotropic molecular mechanisms. Lycopene is one such aliphatic hydrocarbon carotenoid with no...
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Chapter
Plant Genome Editing Technologies: An Updated Overview
A genome is a representation of all the genetic material that forms an organism and is stored in its deoxyribonucleic acid (DNA). Genetic engineering, genome editing, and gene editing are all terms that relate...
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Chapter
Genome-Editing Technologies in Crop Improvement
Global climate change, together with harmful biotic and abiotic factors, is limiting agricultural yields, rendering it challenging to meet the rising need for food supply on a global scale. The development of ...
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Article
Network pharmacology-based anti-colorectal cancer activity of piperlonguminine in the ethanolic root extract of Piper longum L
Colorectal cancer (CRC) has the second highest incidence and fatality rates of any malignancy, at 10.2 and 9.2%, respectively. Plants and plants-based products for thousands of years have been utilized to trea...
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Article
Network pharmacology of apigeniflavan: a novel bioactive compound of Trema orientalis Linn. in the treatment of pancreatic cancer through bioinformatics approaches
Pancreatic cancer is the seventh most prevalent cause of mortality globally. Since time immemorial, plant-derived products have been in use as therapeutic agents due to the existence of biologically active mol...
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Article
Network pharmacology-based anti-pancreatic cancer potential of kaempferol and catechin of Trema orientalis L. through computational approach
In pancreatic cancer, healthy cells in the pancreas begin to malfunction and proliferate out of control. According to our conventional knowledge, many plants contain several novel bioactive compounds, having p...
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Chapter
Gut Microbiome, COVID-19, and Neurological Impairment
The pandemic of COVID-19 caused by SARS-CoV-2 has created havoc worldwide. It causes lung infection through binding of ACE2 receptors that are present on the alveolar epithelial cells. The respiratory infectio...
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Chapter
Microalgal Biomass as a Promising Feedstock for the Production of Biohydrogen: A Comprehensive Review
The global energy crisis and rising greenhouse gas emissions have fueled the search for environmentally acceptable renewable energy sources. Biological hydrogen production from microalgae is a low-cost, clean ...
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Article
Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice
Growth/differentiation factor−15 (Gdf-15) is a member of the transforming growth factor-β (Tgf-β) superfamily and has been shown to be a potent neurotrophic factor for midbrain dopaminergic (DAergic) neurons b...
