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    Immunotherapy in high-risk chemotherapy-resistant patients with metastatic solid tumors and hematological malignancies using intentionally mismatched donor lymphocytes activated with rIL-2: a phase I study

    The feasibility and safety of immunotherapy mediated by intentionally mismatched rIL-2 activated killer lymphocytes (IMAK) with no prior stem cell engraftment was investigated in patients with advanced chemoth...

    Shimon Slavin, Aliza Ackerstein, Reuven Or in Cancer Immunology, Immunotherapy (2010)

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    Interleukin 2 regulation following semi-allogeneic bone marrow transplantation in mice

    Success of allogeneic and autologous bone marrow transplantation (BMT) is hampered by susceptibility to infection during the first two post-treatment years. Further, in treating malignant diseases, impaired an...

    Ali Abdul-Hai, Arie Ben-Yehuda, Haya Galsky in Cancer Immunology, Immunotherapy (2006)

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    Mycophenolate mofetil does not suppress the graft-versus-leukemia effect or the activity of lymphokine-activated killer (LAK) cells in a murine model

    Background: Graft-versus-leukemia (GVL) effect is an essential component in the course of allogeneic stem cell transplantation (SCT). However, both prevention and treatment of established graft-versus-host dis...

    Michael Y. Shapira, Ester Hirshfeld, Lola Weiss in Cancer Immunology, Immunotherapy (2005)

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    Immunotherapy of murine leukemia following non-myeloablative conditioning with naïve or G-CSF mobilized blood or bone marrow stem cells

    Allogeneic stem cell transplantation (SCT) is the treatment of choice for a large number of hematologic malignancies. Its major advantage over conventional chemotherapy lies in the graft-versus-leukemia (GVL) ...

    Lola Weiss, Reuven Or, Shimon Slavin, Ella Naparstek in Cancer Immunology, Immunotherapy (2004)