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  1. Article

    Open Access

    Allo-priming as a universal anti-viral vaccine: protecting elderly from current COVID-19 and any future unknown viral outbreak

    We present the rationale for a novel allo-priming approach to serve the elderly as a universal anti-virus vaccine, as well serving to remodel the aging immune system in order to reverse immunosenescence and in...

    Michael Har-Noy, Reuven Or in Journal of Translational Medicine (2020)

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  2. No Access

    Article

    Enhanced Survival and Neurite Network Formation of Human Umbilical Cord Blood Neuronal Progenitors in Three-Dimensional Collagen Constructs

    Umbilical cord blood (CB) stem cells have been proposed for cell-based therapeutic applications for diverse diseases of the CNS. We hypothesized that tissue-engineering strategies may extend the efficacy of th...

    Marian M. Bercu, Hadar Arien-Zakay, Dana Stoler… in Journal of Molecular Neuroscience (2013)

  3. No Access

    Article

    Anti-T Lymphocyte Globulin (ATG) Induces Generation of Regulatory T Cells, at Least Part of Them Express Activated CD44

    We show here that the anti-T lymphocyte immunoglobulin (ATG) can induce Treg cells following 24-h incubation in human peripheral blood mononuclear cells (PBMCs). The ATG-induced Treg cells express known cell s...

    Orly Shimony, Arnon Nagler, Yechiel N. Gellman… in Journal of Clinical Immunology (2012)

  4. Article

    Open Access

    Neuroblastoma Cell Death is Induced by Inorganic Arsenic Trioxide (As2O3) and Inhibited by a Normal Human Bone Marrow Cell-Derived Factor

    Three phenotypically distinct cell types are present in human neuroblastomas (NB) and NB cell lines: I-type stem cells, N-type neuroblastic precursors, and S-type Schwannian/melanoblastic precursors. The stimu...

    Benjamin Gesundheit, Lea Malach, Reuven Or, Talia Hahn in Cancer Microenvironment (2008)

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  5. No Access

    Article

    Allogeneic stem cell transplantation for the treatment of diseases associated with a deficiency in bone marrow products

    Our understanding of the pathophysiology of hematopoietic failure associated syndromes led to the developmental of potentially curative procedures for the treatment of many diseases including Severe aplastic a...

    Reuven Or, Memet Aker, Michael Yechiel Shapira… in Springer Seminars in Immunopathology (2004)

  6. No Access

    Article

    Treatment of Leukemia by Alloreactive Lymphocytes and Nonmyeloablative Stem Cell Transplantation

    Allogeneic bone marrow or blood stem cell transplantation (BMT) represents an important therapeutic tool for treatment of otherwise incurable malignant and nonmalignant diseases, especially acute and chronic l...

    Shimon Slavin, Arnon Nagler, Michael Y. Shapira… in Journal of Clinical Immunology (2002)