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    Article

    Physiogenomic resources for rat models of heart, lung and blood disorders

    Cardiovascular disorders are influenced by genetic and environmental factors. The TIGR rodent expression web-based resource (TREX) contains over 2,200 microarray hybridizations, involving over 800 animals from...

    Renae L Malek, Hong-ying Wang, Anne E Kwitek, Andrew S Greene in Nature Genetics (2006)

  2. Article

    Addendum: Standardizing global gene expression analysis between laboratories and across platforms

    Theodore Bammler, Richard P Beyer, Sanchita Bhattacharya, Gary A Boorman in Nature Methods (2005)

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    Article

    Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12

    Activated forms of Ras family members are prevalent in many cancers where Ras mutants transduce signals essential for transformation, angiogenesis, invasion and metastasis. As a cancer progression model, we us...

    Hidemi Teramoto, Maria Domenica Castellone, Renae L Malek, Noah Letwin in Oncogene (2005)

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    Article

    Identification of H-Ras, RhoA, Rac1 and Cdc42 responsive genes

    The superfamily of small GTP-binding proteins has expanded dramatically in recent years. The Ras family has long been associated with signaling pathways contributing to normal and aberrant cell growth, while R...

    Hidemi Teramoto, Renae L Malek, Babak Behbahani, Maria Domenica Castellone in Oncogene (2003)

  5. Article

    Assessing unmodified 70-mer oligonucleotide probe performance on glass-slide microarrays

    Long oligonucleotide microarrays are potentially more cost- and management-efficient than cDNA microarrays, but there is little information on the relative performance of these two probe types. The feasibility...

    Hong-Ying Wang, Renae L Malek, Anne E Kwitek, Andrew S Greene in Genome Biology (2003)

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    Article

    Identification of Src transformation fingerprint in human colon cancer

    We used a classical rodent model of transformation to understand the transcriptional processes, and hence the molecular and cellular events a given cell undergoes when progressing from a normal to a transforme...

    Renae L Malek, Rosalyn B Irby, Qingbin M Guo, Kerry Lee, Sylvia Wong, Mei He in Oncogene (2002)

  7. Article

    Use of the Rat Gene Index to examine gene expression patterns from Src-transformed rat fibroblasts that exhibit broad differences in metastatic potential

    Renae L. Malek, Qingbin Guo, Mauro Ruffy, Edison T. Liu, Ingeborg Holt in Nature Genetics (1999)