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Article
Crosstalking second messengers
By competing for the same binding site on SmbA, a regulatory nucleotide-binding protein, the bacterial second messengers c-di-GMP and (p)ppGpp inversely balance cell cycle re-entry of growth-arrested swarmer c...
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Article
Journal Club
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Chapter
Cellulose in Bacterial Biofilms
Many bacteria produce cellulose as an exopolysaccharide component of the extracellular matrix in biofilms, which are large aggregates of bacterial cells often attached to abiotic or biotic surfaces. Cellulose ...
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Protocol
Experimental Detection and Visualization of the Extracellular Matrix in Macrocolony Biofilms
By adopting elaborate three-dimensional morphologies that vary according to their extracellular matrix composition, macrocolony biofilms offer a unique opportunity to interrogate about the roles of specific ma...
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Article
Bakterielle Megastädte
What makes a multicellular aggregate of bacterial cells a biofilm is the presence of an extracellular polymeric matrix. Besides being protective, matrix components such as amyloid curli fibres and cellulose in Es...
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Article
Open AccessLogical-continuous modelling of post-translationally regulated bistability of curli fiber expression in Escherichia coli
Bacteria have developed a repertoire of signalling mechanisms that enable adaptive responses to fluctuating environmental conditions. The formation of biofilm, for example, allows persisting in times of extern...
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Article
Principles of c-di-GMP signalling in bacteria
Bis-(3′-5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) is a ubiquitous bacterial second-messenger molecule that is involved in the molecular decision be...
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Chapter
The Two-Component Network and the General Stress Sigma Factor RpoS (σS) in Escherichia coli
The general stress sigma factor RpoS (σs) is induced buring entry into stationary phase and in response to multiple stress conditions. RpoS is regulated at the levels of transcription, translation, proteolysis an...
