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Transitional dendritic cells are distinct from conventional DC2 precursors and mediate proinflammatory antiviral responses
High-dimensional approaches have revealed heterogeneity amongst dendritic cells (DCs), including a population of transitional DCs (tDCs) in mice and humans. However, the origin and relationship of tDCs to othe...
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Article
Open AccessCD70 expression determines the therapeutic efficacy of expanded human regulatory T cells
Regulatory T cells (Tregs) are critical mediators of immune homeostasis. The co-stimulatory molecule CD27 is a marker of highly suppressive Tregs, although the role of the CD27-CD70 receptor-ligand interaction...