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Chapter
Key Age-Imposed Signaling Changes That Are Responsible for the Decline of Stem Cell Function
This chapter analyzes recent developments in the field of signal transduction of ageing with the focus on the age-imposed changes in TGF-beta/pSmad, Notch, Wnt/beta-catenin, and Jak/Stat networks. Specifically...
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Article
Open AccessA single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood
Heterochronic parabiosis rejuvenates the performance of old tissue stem cells at some expense to the young, but whether this is through shared circulation or shared organs is unclear. Here we show that heteroc...