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    Chapter

    Key Age-Imposed Signaling Changes That Are Responsible for the Decline of Stem Cell Function

    This chapter analyzes recent developments in the field of signal transduction of ageing with the focus on the age-imposed changes in TGF-beta/pSmad, Notch, Wnt/beta-catenin, and Jak/Stat networks. Specifically...

    Melod Mehdipour, Yutong Liu, Chao Liu in Biochemistry and Cell Biology of Ageing: P… (2018)

  2. Article

    Open Access

    A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood

    Heterochronic parabiosis rejuvenates the performance of old tissue stem cells at some expense to the young, but whether this is through shared circulation or shared organs is unclear. Here we show that heteroc...

    Justin Rebo, Melod Mehdipour, Ranveer Gathwala, Keith Causey in Nature Communications (2016)