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Article
Open AccessBlood biomarker-based classification study for neurodegenerative diseases
As the population ages, neurodegenerative diseases are becoming more prevalent, making it crucial to comprehend the underlying disease mechanisms and identify biomarkers to allow for early diagnosis and effect...
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Article
Open AccessBayesian statistics in the design and analysis of cluster randomised controlled trials and their reporting quality: a methodological systematic review
In a cluster randomised controlled trial (CRCT), randomisation units are “clusters” such as schools or GP practices. This has methodological implications for study design and statistical analysis, since cluste...
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Article
Open AccessGene expression meta-analysis of Parkinson’s disease and its relationship with Alzheimer’s disease
Parkinson’s disease (PD) and Alzheimer’s disease (AD) are the most common neurodegenerative diseases and have been suggested to share common pathological and physiological links. Understanding the cross-talk b...
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Article
A Coupled Calibration and Modelling Approach to the Understanding of Dry-Land Lake Oxygen Isotope Records
Comparisons between climate proxies and instrumental records through the last two centuries are often used to understand better the controls on palaeoarchives and to find relationships that can be used to quan...