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Article
HETEROGENEITY OF SEVERE COMBINED IMMUNODEFICIENCY DISEASE (SCID); DEMONSTRATION OF PUTATIVE GAMMA CHAIN T CELL RECEPTOR
The syndrome of SCID represents a heterogenous group of congenital lethal disorders, characterized by defects of both T and B cell systems. The patient was an eight month old female who had normal numbers of B...
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Article
LYMPHOCYTE POPULATION AND FUNCTION IN PERTUSSIS
Lymphocytosis is frequently associated with clinical pertussis. Lymphocyte population in 10 children with bacteriologically proven pertussis was studied. The total number of lymphocytes, T and B cells, mitogen...
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Article
Immunoregulatory properties of childhood leukemias
Investigation ofin vitro humoral immune responses and immunoregulatory properties of leukemic cell was carried out in 17 children with acute leukemia prior to therapy. Leukemias were of the non-T, non-B-cell type...
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Article
Polyclonal and antigen-specific B-Cell responses in patients with common variable immunodeficiency
Antigen-specific antibody responses were investigated in 32 hypogammaglobulinemic patients with common variable immunodeficiency followingin vitro sensitization of their peripheral blood lymphocyte cultures with ...
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Article
848 LOSS OF HELPER CELL FUNCTION IN AELASTIC ANEMIA
Ficoll-Hypaque separated marrow cells from 16 patients and normal volunteers were cultured in soft agar for CFU-c (colony forming units). Marrow cells were further fractionated by velocity sedimentation at uni...
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Chapter
Primary Immunodeficiency Diseases of Man
Study of the primary immunodeficiency diseases has had major consequences for the practice of medicine. New knowledge of the mechanisms responsible for these disorders has contributed not only to our ability t...
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Chapter
Therapeutic Approaches to Immunological Diseases
In the last century, a series of great discoveries has revolutionized medical inquiry and treatment. Our profession has entered a new epoch, approaching the body’s systems and interacting mechanisms no longer ...
