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  1. No Access

    Article

    Recurrent inactivating RASA2 mutations in melanoma

    Yardena Samuels and colleagues report the analysis of 501 melanoma exomes and the identification of RASA2 as a tumor-suppressor gene mutated in 5% of melanomas. RASA2 mutations led to increased RAS activation, an...

    Rand Arafeh, Nouar Qutob, Rafi Emmanuel, Alona Keren-Paz, Jason Madore… in Nature Genetics (2015)

  2. No Access

    Article

    YAP and the drug resistance highway

    Deciphering mechanisms of drug resistance is crucial to winning the battle against cancer. A new study points to an unexpected function of YAP in drug resistance and illuminates its potential role as a therape...

    Alona Keren-Paz, Rafi Emmanuel, Yardena Samuels in Nature Genetics (2015)