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Open AccessManChEWS: Royal Manchester Children's Hospital early warning score
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The pharmacokinetics of the antimigraine compound zolmitriptan in Japanese and Caucasian subjects
Abstract
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Persistent pulmonary hypertension of the term neonate: a strategy for management
The management of 32 consecutive term infants referred with persistent pulmonary hypertension of the newborn were reviewed. Despite indices suggesting severe cardiorespiratory failure with a median alveolar-a...
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Acute hypoxemic respiratory failure in children: case mix and the utility of respiratory severity indices
Objective: Acute hypoxemic respiratory failure (AHRF) is a common reason for emergency pediatric intensive care. An objective assessment of disease severity from acute physiological parameters wo...
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The Metabolism of Zolmitriptan
Two studies were conducted in healthy volunteers to evaluate the effects of rifampicin and cimetidine on the pharmacokinetics of the oral antimigraine compound zolmitriptan. Each study was an open, randomised,...
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Time course of central nervous dopamine-D2 and 5-HT2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel®) in patients with schizophrenia
Quetiapine (Seroquel) is a novel antipsychotic with an atypical profile in animal models and a relatively short plasma half-life of 2.5–5 h. In the present study, we used PET to compare the time course of blo...
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Acute lung injury/Airway
