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Article
Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome
Epigenetic mechanisms underlying tumorigenesis have recently received much attention as potential therapeutic targets of human cancer. We designed a pilot study to target DNA methylation and histone deacetylat...
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Chapter and Conference Paper
X-Ray Microscopy Studies on the Pharmaco-Dynamics of Therapeutic Gallium in Rat Bones
Since the original observation of exogenous gallium accumulation in bones ANGHILERI et al. [1], several studies have demonstrated that gallium nitrate is extremely effective in preserving bone mineral content ...
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Chapter
Clinical Studies of New Anthracycline Analogs
Daunorubicin and doxorubicin (or adriamycin) are among the most important of our current cancer chemotherapeutic drugs. They are key components in current therapy of acute leukemia, malignant lymphoma, breast ...