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Chapter and Conference Paper
Binding Patterns of the Monoclonal Antibodies in the 10th Workshop 2-D Gel Analysis of Class II Antigens
The monoclonal antibodies used for the Workshop two-dimensional (2-D) gel study were selected to satisfy several criteria. In order to use them for the 2-D gel study and the study of alloreactive T-cell clones...
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Chapter and Conference Paper
Computerized Analysis of 2-D Gel Patterns of the HLA Class II Antigens
One goal of the 10th Workshop 2-D gel analysis of HLA class II antigens was to evaluate whether computer programs could be used to compare patterns more objectively than by visual analysis alone. In a previous...
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Chapter and Conference Paper
HLA Class II Alloantigens Defined by Cytotoxic T Cell Clones and Monoclonal Antibodies
Biochemical studies of HLA-DQ molecules have revealed polymorphisms which have not been previously recognized with alloantisera. HLA-DQ molecules from individuals homozygous for DR1, DR2, or DRw6 can all be di...
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Chapter and Conference Paper
A Supertypic DRw53 Determinant is Carried on the HLA-DR Subset of Class II Molecules on HLA-DR7 Cell Lines
The HLA class II molecules carrying a supertypic DRw53 determinant have been characterized in biochemical studies through the use of the monoclonal antibody (mAb) PL3. This mAb binds specifically to all DR4, D...
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Chapter and Conference Paper
Analysis of T Lymphocyte Antibody Specificities: Comparison of Serology with Immunoprecipitation Patterns
Identification of several distinct cell surface molecules expressed by human T lymphocytes has been made by the use of murine monoclonal antibodies (MoAb) developed against lymphoid cells [2, 3, 5, 13]. The pu...
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Chapter and Conference Paper
Biochemical Analysis of Human Thymus Leukemia-Like Antigens
Two human thymocyte antigens have been identified, using monoclonal antibodies (MoAb), which have a tissue distribution and a molecular structure suggesting that they may be the human equivalents of the murine...
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Chapter and Conference Paper
Serological Analysis of Two Monoclonal Antibodies: One Detecting an DRw53 Supertypic Determinant and One Detecting a New Supertypic Determinant Related to HLA-DR7
Two cytotoxic monoclonal antibodies (MoAbs), PL3 (IgG3) and PL2 (IgG2a), were produced by immunization with an HLA-DR7 homozygous cell line, PLH. Their serological specificities were determined by binding assa...
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Article
Detection of human cancer in an animal model using radio-labelled tumour-associated monoclonal antibodies
Monoclonal antibodies to epithelial-cell antigenic determinants, labelled with 123I and 125I, were administered parenterally to immunodeficient mice bearing human tumours derived from a human cancer cell line....
