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  1. No Access

    Article

    Fumonisins: current research trends in developmental toxicology

    Fumonisin B1 (FB1) is a mycotoxin produced byFusarium verticillioides that is found in maize and maize-based foods. Reproductive studies in CD1 mice, rats and rabbits initially found no evidence that fumonisins a...

    K. A. Voss, J. B. Gelineau-van Waes, R. T. Riley in Mycotoxin Research (2006)

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    Article

    Fumonisin hepatotoxicity is reduced in mice carrying the human tumour necrosis factor α transgene

    Our previous studies have indicated that tumour necrosis factor α (TNFα) is involved in fumonisin B1 (FB1)-induced toxic responses. To investigate the role of TNFα in FB1 toxicity further we employed male transg...

    Raghubir P. Sharma, Neetesh Bhandari, Masashi Tsunoda, R.T. Riley… in Archives of Toxicology (2000)

  3. No Access

    Chapter

    Fumonisin Toxicity and Sphingolipid Biosynthesis

    Fumonisins are inhibitors of sphinganine (sphingosine) N-acyltransferase (ceramide synthase) in vitro, and exhibit competitive-type inhibition with respect to both substrates of this enzyme (sphinganine and fatty...

    A. H. Merrill Jr., E. Wang, T. R. Vales, E. R. Smith, J. J. Schroeder… in Fumonisins in Food (1996)

  4. No Access

    Chapter

    Mechanisms of Mycotoxicity

    One reason to study mechanisms of action of mycotoxins is to reveal the initial biochemical lesions leading to the progression of diseases associated with consumption of mycotoxin-contaminated foods and feeds....

    R. T. Riley, W. P. Norred in Human and Animal Relationships (1996)

  5. No Access

    Chapter

    The Chemistry and Biological Activities of the Natural Products AAl-Toxin and the Fumonisins

    The fumonisins and AAL-toxin are structurally-related natural products produced by fungi (22, 23, 24). Fumonisin B1 [FB1] has been recognized since 1988 as a mammalian toxin (36, 37, 44, 52). More recently, FB1 h...

    H. K. Abbas, S. O. Duke, W. T. Shier, R. T. Riley, G. A. Kraus in Natural Toxins 2 (1996)

  6. No Access

    Article

    Introduction

    R. T. Riley, J. L. Richard in Mycopathologia (1992)

  7. No Access

    Chapter

    Mycotoxin-Induced Alterations in Ion Transport Across Cell Membranes

    Patulin and cyclopiazonic acid are fungal metabolites produced by certain species of Penicillium and Aspergillus. Patulin is also produced by certain Byssochlamys species. Both compounds are known to contaminate ...

    R. T. Riley, D. E. Goeger, D. M. Hintona in Microbial Toxins in Foods and Feeds (1990)

  8. No Access

    Chapter

    Lipophilic Cations as Membrane Probes in Cultured Renal (LLC-PK1) and Muscle Cells (L6)

    Tetraphenylphosphonium (TPP) and triphenylmethylphosphonium (TPMP) are lipophilic cations which have been used to measure transmembrane potentials in vesicles, mitochondria, and plant and animal cells (Cafimo ...

    R. T. Riley, D. E. Goeger, W. P. Norred in Nephrotoxicity (1989)

  9. No Access

    Article

    Transport of naphthalene in the oyster Ostrea edulis

    In small oysters (Ostrea edulis), transport of naphthalene between tissues is primarily by diffusion and not via the circulatory system. In intact oysters, accumulation in the adductor muscle and body followed ac...

    R. T. Riley, M. A. Shirazi, R. C. Swartz in Marine Biology (1981)

  10. No Access

    Article

    Uptake and accumulation of naphthalene by the oyster Ostrea edulis, in a flow-through system

    A flow-through system was used to follow naphthalene and naphthalene metabolite accumulation in the seawater and in the tissue of the oyster Ostrea edulis. After 72 h, 82.5% of the naphthalene carbon was recovere...

    R. T. Riley, M. C. Mix, R. L. Schaffer, D. L. Bunting in Marine Biology (1981)