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Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity

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  1. Article

    Open Access

    The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells

    Several lines of evidence have suggested that stemness and acquired resistance to targeted inhibitors or chemotherapeutics are mechanistically linked. Here we observed high cell surface and total levels of ner...

    T Redmer, I Walz, B Klinger, S Khouja, Y Welte, R Schäfer, C Regenbrecht in Oncogenesis (2017)

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  2. Article

    Open Access

    Uncoupling of EGFR–RAS signaling and nuclear localization of YBX1 in colorectal cancer

    The transcription factor YBX1 can act as a mediator of signals transmitted via the EGFR–RAS–MAPK axis. YBX1 expression has been associated with tumor progression and prognosis in multiple types of cancer. Immu...

    F Roßner, C Gieseler, M Morkel, H-D Royer, M Rivera, H Bläker, M Dietel… in Oncogenesis (2016)

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